anti-CRH / Corticotropin Releasing Factor antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG43713
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes CRH / Corticotropin Releasing Factor |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CRH / Corticotropin Releasing Factor |
| 抗原物种 | Human |
| 抗原 | Recombinant protein sequence corresponding to the a.a. 25-194 of Human CRF protein. |
| 偶联标记 | Un-conjugated |
| Protein Full name | Corticoliberin |
| 別名 | CRH; Corticoliberin; Corticotropin-releasing hormone; CRF; CRH1; Corticotropin-releasing factor |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 实际分子量 | 25-30 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS (pH7.3), 0.02% Sodium azide and 50% Glycerol |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CRH |
| 全名 | corticotropin releasing hormone |
| 背景介绍 | Corticotropin-releasing hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Marked reduction in this protein has been observed in association with Alzheimer disease and autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta. In the placenta it is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of the hormone occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, this protein may act as a trigger for parturition. [provided by RefSeq, Apr 2010] |
| 生物功能 | This hormone from hypothalamus regulates the release of corticotropin from pituitary gland. [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
| 预测分子量 | 21.4 kDa |
| 翻译后修饰 | Amidation, Cleavage on pair of basic residues |
检测图片 (3)
ARG43713 anti-CRH / Corticotropin Releasing Factor antibody WB image
Western blot: SHSY5Y cell lysate stained with ARG43713 anti-CRH / Corticotropin Releasing Factor antibody.
ARG43713 anti-CRH / Corticotropin Releasing Factor antibody WB image
Western blot: Rat brain tissue lysate stained with ARG43713 anti-CRH / Corticotropin Releasing Factor antibody.
ARG43713 anti-CRH / Corticotropin Releasing Factor antibody WB image
Western blot: Mousebrain tissue lysate stained with ARG43713 anti-CRH / Corticotropin Releasing Factor antibody.
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