anti-CRHBP antibody
CAT.NO. : ARG59582
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概述
产品描述 | Rabbit Polyclonal antibody recognizes CRHBP |
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反应物种 | Hu, Ms, Rat |
应用 | ICC/IF, IHC-P, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | CRHBP |
抗原物种 | Human |
抗原 | Recombinant fusion protein corresponding to aa. 25-322 of Human CRHBP (NP_001873.2). |
偶联标记 | Un-conjugated |
別名 | CRFBP; CRH-BP; CRF-binding protein; Corticotropin-releasing hormone-binding protein; Corticotropin-releasing factor-binding protein; CRF-BP |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
阳性对照 | Rat brain | ||||||||
实际分子量 | 37 kDa |
属性
形式 | Liquid |
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纯化 | Affinity purified. |
缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 50% Glycerol |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # P24387 Human Corticotropin-releasing factor-binding protein Swiss-port # Q60571 Mouse Corticotropin-releasing factor-binding protein |
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基因名称 | CRHBP |
全名 | corticotropin releasing hormone binding protein |
背景介绍 | Corticotropin-releasing hormone is a potent stimulator of synthesis and secretion of preopiomelanocortin-derived peptides. Although CRH concentrations in the human peripheral circulation are normally low, they increase throughout pregnancy and fall rapidly after parturition. Maternal plasma CRH probably originates from the placenta. Human plasma contains a CRH-binding protein which inactivates CRH and which may prevent inappropriate pituitary-adrenal stimulation in pregnancy. [provided by RefSeq, Jul 2008] |
生物功能 | Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. [UniProt] |
细胞定位 | Secreted. [UniProt] |
预测分子量 | 36 kDa |
