anti-CRLS1 antibody
CAT.NO. : ARG42094
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概述
产品描述 | Goat Polyclonal antibody recognizes CRLS1 |
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反应物种 | Hu |
预测物种 | Ms, Rat, Cow, Dog, Pig |
应用 | IHC-P, WB |
特异性 | This antibody is expected to recognize both reported isoforms (NP_061968.1; NP_001120930.1). |
宿主 | Goat |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | CRLS1 |
抗原物种 | Human |
抗原 | Synthetic peptide around the internal region of Human CRLS1. (C-RSALGSALDPLADK) (NP_061968.1; NP_001120930.1) |
偶联标记 | Un-conjugated |
別名 | CLS; CLS1; GCD10; C20orf155; dJ967N21.6; Cardiolipin synthase (CMP-forming); CLS; EC 2.7.8.41; Protein GCD10 homolog |
应用说明
应用建议 |
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应用说明 | WB: Recommend incubate at RT for 1h. IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
阳性对照 | HEK293 | ||||||
实际分子量 | ~ 33 kDa |
属性
形式 | Liquid |
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纯化 | Ammonium sulphate precipitation followed by affinity purification with immunogen. |
缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 0.5% BSA |
浓度 | 0.5 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # Q9UJA2 Human Cardiolipin synthase (CMP-forming) |
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基因名称 | CRLS1 |
全名 | cardiolipin synthase 1 |
背景介绍 | This gene encodes a member of the CDP-alcohol phosphatidyltransferase class-I family of proteins. The encoded enzyme catalyzes the synthesis of cardiolipin, a phospholipid component of mitochondrial membranes that is critical for mitochondrial function. [provided by RefSeq, Apr 2016] |
生物功能 | Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions. [UniProt] |
细胞定位 | Mitochondrion inner membrane; Multi-pass membrane protein. [UniProt] |
预测分子量 | 33 kDa |
检测图片 (2)
ARG42094 anti-CRLS1 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human kidney tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG42094 anti-CRLS1 antibody at 5 µg/ml dilution.
ARG42094 anti-CRLS1 antibody WB image
Western blot: 35 µg of HEK293 cell lysate (in RIPA buffer) stained with ARG42094 anti-CRLS1 antibody at 0.2 µg/ml dilution and incubated at RT for 1 hour.
