anti-CtBP1 antibody [4D6]

CAT.NO. : ARG57107

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Size:

50 μl

*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	Mouse Monoclonal antibody [4D6] recognizes CtBP1
反应物种	Hu
应用	WB
宿主	Mouse
克隆	Monoclonal
克隆号	4D6
同位型	IgG2b, kappa
靶点名称	CtBP1
抗原物种	Human
抗原	Recombinant fragment around aa. 1-440 of Human CtBP1
偶联标记	Un-conjugated
別名	EC 1.1.1.-; CtBP1; BARS; C-terminal-binding protein 1

应用说明

应用建议

应用	推荐稀释比
WB	1:500

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purification with Protein G.
缓冲液	PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	10% Glycerol
浓度	1 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 1487 Human CTBP1 Swiss-port # Q13363 Human C-terminal-binding protein 1
基因名称	CTBP1
全名	C-terminal binding protein 1
背景介绍	This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]
生物功能	Corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. Has dehydrogenase activity. Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation. [UniProt]
预测分子量	48 kDa
翻译后修饰	The level of phosphorylation appears to be regulated during the cell cycle. Phosphorylation by HIPK2 on Ser-422 induces proteasomal degradation. ADP-ribosylated; when cells are exposed to brefeldin A. Sumoylation on Lys-428 is promoted by the E3 SUMO-protein ligase CBX4.

检测图片 (1)

ARG57107 anti-CtBP1 antibody [4D6] WB image
Western blot: 40 µg of 1) HeLa, 2) NIH3T3, 3) 293T, 4) AGS, 5) Raji, 6) A549, and 7) Jurkat cell lysates stained with ARG57107 anti-CtBP1 antibody [4D6] at 1:500.

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