anti-CXCL2 / MIP2 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes CXCL2 / MIP2
  • 反应物种: Ms, Rat
  • 应用: ELISA, Neut, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: CXCL2 / MIP2
  • 抗原物种: Mouse
  • 抗原: E.coli derived Recombinant Mouse MIP-2 (CXCL2).(AVVASELRCQ CLKTLPRVDF KNIQSLSVTP PGPHCAQTEV IATLKGGQKV CLDPEAPLVQ KIIQKILNKG KAN)
  • Brand:
CAT.NO. : ARG56661
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes CXCL2 / MIP2
反应物种Ms, Rat
应用ELISA, Neut, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称CXCL2 / MIP2
抗原物种Mouse
抗原E.coli derived Recombinant Mouse MIP-2 (CXCL2).
(AVVASELRCQ CLKTLPRVDF KNIQSLSVTP PGPHCAQTEV IATLKGGQKV CLDPEAPLVQ KIIQKILNKG KAN)
偶联标记Un-conjugated
別名Gro-beta; SCYB2; HSF; CINC-2a; GROb; MGSA-b; SB-251353; MIP2A; MIP2; Hematopoietic synergistic factor; 5-73; C-X-C motif chemokine 2; MIP-2a; GRO2; Macrophage inflammatory protein 2-alpha; GRO-beta-T; Growth-regulated protein beta; MIP2-alpha
应用说明
应用建议
应用推荐稀释比
ELISASandwich: 0.5 - 2.0 µg/ml with ARG56771 as a detection antibody
Neut0.52 - 0.90 µg/ml (To yield [ND50] of the biological activity of mMIP - 2 (15.00 ng/ml) )
WB0.1 - 0.2 µg/ml
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液PBS (pH 7.2)
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 114105 Rat CXCL2

GeneID: 20310 Mouse CXCL2

Swiss-port # P10889 Mouse C-X-C motif chemokine 2

Swiss-port # P30348 Rat C-X-C motif chemokine 2

基因名称Cxcl2
全名chemokine (C-X-C motif) ligand 2
背景介绍This antimicrobial gene is part of a chemokine superfamily that encodes secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CXC subfamily, is expressed at sites of inflammation and may suppress hematopoietic progenitor cell proliferation. [provided by RefSeq, Sep 2014]
生物功能Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity. [UniProt]
预测分子量11 kDa
翻译后修饰The N-terminal processed form GRO-beta(5-73) is produced by proteolytic cleavage after secretion from bone marrow stromal cells.
检测图片 (3)
  • ARG56661 anti-CXCL2 / MIP2 antibody WB image

    Western blot: 250 - 0.24 ng of Mouse MIP-2 stained with ARG56661 anti-CXCL2 / MIP2 antibody, under reducing conditions.

  • ARG56661 anti-CXCL2 / MIP2 antibody WB image

    Western blot: 250 - 0.24 ng of Mouse MIP-2 stained with ARG56661 anti-CXCL2 / MIP2 antibody, under non-reducing conditions.

  • ARG56661 anti-CXCL2 / MIP2 antibody standard curve image

    Sandwich ELISA: ARG56661 anti-CXCL2 / MIP2 antibody as a capture antibody at 0.5 - 2.0 µg/ml combined with ARG56771 anti-CXCL2 / MIP-2 antibody (Biotin) as a detection antibody. Results of a typical standard run with optical density.

参考文献

Self-recruited neutrophils trigger over-activated innate immune response and phenotypic change of cardiomyocytes in fulminant viral myocarditis

Neut / Mouse

Huihui Li et al.
Cell discovery,  (2023)

publication_link

 

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