anti-CXCR7 / CD187 antibody [10D1-J16] (APC)

CAT.NO. : ARG44607

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Size:

100 tests

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Product Details

概述

产品描述	APC-conjugated Mouse Monoclonal antibody recognizes CXCR7 / CD187
反应物种	Hu
应用	FACS
宿主	Mouse
克隆	Monoclonal
克隆号	10D1-J16
同位型	IgG2a kappa
靶点名称	CXCR7 / CD187
抗原物种	Human
偶联标记	APC
別名	ACKR3; Atypical Chemokine Receptor 3; GPR159; RDC1; Chemokine Orphan Receptor 1; CMKOR1; CXCR7; G-Protein Coupled Receptor RDC1 Homolog; Chemokine (C-X-C Motif) Receptor 7; C-X-C Chemokine Receptor Type 7 ; G-Protein Coupled Receptor 159; CXC-R7; CXCR-7; RDC-1; G Protein-Coupled Receptor

应用说明

应用建议

应用	推荐稀释比
FACS	10 µl / 100 µl or 10^6 cells

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purified antibody is conjugated with activated allophycocyanin (APC), and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
缓冲液	PBS (pH 7.4) and 15 mM Sodium azide
抗菌剂	15 mM Sodium azide
存放说明	Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 57007 Human ACKR3 Swiss-port # P25106 Human Atypical chemokine receptor 3
基因名称	ACKR3
全名	Atypical Chemokine Receptor 3
背景介绍	This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas. [provided by RefSeq, Jul 2008]
生物功能	Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Acts as a receptor for chemokines CXCL11 and CXCL12/SDF1. [Uniprot]
细胞定位	Cell membrane, Endosome, Membrane. [Uniprot]
预测分子量	41 kDa
翻译后修饰	Disulfide bond, Glycoprotein, Phosphoprotein, Ubl conjugation. [Uniprot]

检测图片 (1)

ARG44607 anti-CXCR7 / CD187 antibody [10D1-J16] (APC) FACS image
Flow Cytometry: MCF-7 stained with ARG44607 anti-CXCR7 / CD187 antibody [10D1-J16] (APC) at 10 μl/ 100 μl dilution.

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