anti-CXCR7 / CD187 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes CXCR7 / CD187
  • 反应物种: Hu, Ms
  • 预测物种: Rat
  • 应用: WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: CXCR7 / CD187
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG56565
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes CXCR7 / CD187
反应物种Hu, Ms
预测物种Rat
应用WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称CXCR7 / CD187
抗原物种Human
抗原Recombinant protein of Human CXCR7.
偶联标记Un-conjugated
別名ACKR3; Atypical Chemokine Receptor 3; GPR159; RDC1; Chemokine Orphan Receptor 1; CMKOR1; CXCR7; G-Protein Coupled Receptor RDC1 Homolog; Chemokine (C-X-C Motif) Receptor 7; C-X-C Chemokine Receptor Type 7 ; G-Protein Coupled Receptor 159; CXC-R7; CXCR-7; RDC-1; G Protein-Coupled Receptor
应用说明
应用建议
应用推荐稀释比
WB1:500 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 12778 Mouse ACKR3

GeneID: 57007 Human ACKR3

Swiss-port # P25106 Human Atypical chemokine receptor 3

Swiss-port # P56485 Mouse Atypical chemokine receptor 3

基因名称ACKR3
全名atypical chemokine receptor 3
背景介绍This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas. [provided by RefSeq, Jul 2008]
生物功能Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Acts as a receptor for chemokines CXCL11 and CXCL12/SDF1. [Uniprot]
细胞定位Cell membrane, Endosome, Membrane. [Uniprot]
预测分子量41 kDa
翻译后修饰Disulfide bond, Glycoprotein, Phosphoprotein, Ubl conjugation. [Uniprot]
检测图片 (1)
  • ARG56565 anti-CXCR7 / CD187 antibody WB image

    Western blot: 30 µg of MCF7, HeLa, and 3T3 cell lysates stained with ARG56565 anti-CXCR7 / CD187 antibody at 1:500 dilution.

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