anti-Cytochrome P450 26A1 antibody
Key features and details
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- 反应物种:
- 应用:
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- 克隆:
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- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG41346
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Cytochrome P450 26A1 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Cytochrome P450 26A1 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide within aa. 50-150 of Human Cytochrome P450 26A1 (NP_000774.2). |
| 偶联标记 | Un-conjugated |
| 別名 | Cytochrome P450 26A1; CYP26; P450RAI1; Retinoic acid-metabolizing cytochrome; hP450RAI; Retinoic acid 4-hydroxylase; P450RAI; Cytochrome P450 retinoic acid-inactivating 1; CP26; Cytochrome P450RAI; EC 1.14.-.- |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | HepG2 | ||||
| 实际分子量 | 55 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CYP26A1 |
| 全名 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| 背景介绍 | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein acts on retinoids, including all-trans-retinoic acid (RA), with both 4-hydroxylation and 18-hydroxylation activities. This enzyme regulates the cellular level of retinoic acid which is involved in regulation of gene expression in both embryonic and adult tissues. Two alternatively spliced transcript variants of this gene, which encode the distinct isoforms, have been reported. [provided by RefSeq, Jul 2008] |
| 生物功能 | Plays a key role in retinoic acid metabolism. Acts on retinoids, including all-trans-retinoic acid (RA) and its stereoisomer 9-cis-RA. Capable of both 4-hydroxylation and 18-hydroxylation. Responsible for generation of several hydroxylated forms of RA, including 4-OH-RA, 4-oxo-RA and 18-OH-RA. [UniProt] |
| 细胞定位 | Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein. [UniProt] |
| 预测分子量 | 56 kDa |
检测图片 (1)
ARG41346 anti-Cytochrome P450 26A1 antibody WB image
Western blot: 25 µg of HepG2 cell lysate stained with ARG41346 anti-Cytochrome P450 26A1 antibody at 1:1000 dilution.
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