anti-Cytochrome P450 2E1 antibody
CAT.NO. : ARG54452
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概述
产品描述 | Rabbit Polyclonal antibody recognizes Cytochrome P450 2E1 |
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反应物种 | Hu, Ms, Rat, Dog, Gpig, Hrs, Mk, Rb |
应用 | WB |
特异性 | This antibody recognizes human, mouse, rat, rabbit, canine, guinea pig, horse and monkey cytochrome P450 2E1. |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | Cytochrome P450 2E1 |
抗原物种 | Rat |
抗原 | Native Rat cytochrome P450 2E1 |
偶联标记 | Un-conjugated |
別名 | EC 1.14.13.n7; Cytochrome P450 2E1; Cytochrome P450-J; EC 1.14.13.-; P450C2E; CYPIIE1; CYP2E; 4-nitrophenol 2-hydroxylase; P450-J; CPE1 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
阳性对照 | Human, Mouse and Rat liver microsome extract |
属性
形式 | Liquid |
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纯化 | Protein A-purified |
缓冲液 | PBS, 0.09% Sodium azide and 50% Glycerol |
抗菌剂 | 0.09% Sodium azide |
稳定剂 | 50% Glycerol |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | Cyp2e1 |
全名 | cytochrome P450, family 2, subfamily e, polypeptide 1 |
背景介绍 | Cytochrome P450 is a highly conserved, diverse family of heme-containing proteins that function in the metabolism of numerous endogenous and exogenous substrates: organic solvents, acetaminophen, dimethylnitrosamine, aliphatic alcohols, and other potentially toxic compounds for humans.Cytochrome P450 is found mainly in liver but also is found in other organs. It is primarily localized to the inner membranes of mitochondria and the endoplasmic reticulum. Eukaryotic microsomal cytochrome P450 enzymes accept electrons from the FAD- and FMN-containing enzyme NADPH:cytochrome P450 reductase. |
生物功能 | Metabolizes several precarcinogens, drugs, and solvents to reactive metabolites. [UniProt] |
研究领域 | Cell Biology and Cellular Response antibody; Metabolism antibody; Signaling Transduction antibody |
预测分子量 | 57 kDa |
