anti-Cytokeratin (pan) antibody [PAN-CK]
![anti-Cytokeratin (pan) antibody [PAN-CK]](/upload/image/products/ARG56128_IHC_1_210_205.jpg)
![anti-Cytokeratin (pan) antibody [PAN-CK]](/upload/image/products/ARG56128_IHC_1.jpg)
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 特异性:
- 宿主:
- 克隆:
- 克隆号:
- 同位型:
- 靶点名称:
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Brand:
CAT.NO. : ARG56128
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Product Details
概述
| 产品描述 | Mouse Monoclonal antibody [PAN-CK] recognizes Cytokeratin (pan) |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, IHC-P |
| 特异性 | Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, which include CK1, CK3, CK4, CK5, CK6, CK7, CK8, CK10, CK13, CK14, CK15, CK16, CK17, CK18 and CK19. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | PAN-CK |
| 同位型 | IgG, kappa |
| 靶点名称 | Cytokeratin (pan) |
| 抗原物种 | Human |
| 抗原 | Human epidermal keratin |
| 偶联标记 | Un-conjugated |
| 別名 | Type-II keratin Kb39; KRT1B; Keratin-77; K1B; K77; CK-1B; Cytokeratin-1B; Keratin, type II cytoskeletal 1b |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | IHC-P: Antigen Retrieval: Boil tissue section in 10 mM Citrate buffer (pH 6.0) for 10-20 min, followed by cooling at RT for 20 min. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS (pH 7.4), 0.05% Sodium azide and 0.1 mg/ml BSA |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 0.1 mg/ml BSA |
| 浓度 | 0.2 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | KRT77 |
| 全名 | keratin 77, type II |
| 背景介绍 | Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene encodes an epithelial keratin that is expressed in the skin and eccrine sweat glands. The type II keratins are clustered in a region of chromosome 12q13. [provided by RefSeq, Jun 2009] |
| 预测分子量 | 67 kDa (CK1); 64 kDa (CK3); 59 kDa (CK4); 58 kDa (CK5); 56 kDa (CK6); 55 kDa (CK7); 52 kDa (CK8); 56.5 kDa (CK10); 53 kDa (CK13); 50 kDa (CK14); 50 kDa (CK15); 48 kDa (CK16); 46 kDa (CK17); 45 kDa (CK18) and 40 kDa (CK19). |
| 翻译后修饰 | Undergoes deimination of some arginine residues (citrullination). |
检测图片 (1)
ARG56128 anti-Cytokeratin (pan) antibody [PAN-CK] IHC-P image
Immunohistochemistry: Formalin-fixed, paraffin-embedded Human skin stained with ARG56128 anti-Cytokeratin (pan) antibody [PAN-CK].
参考文献
Long-term remission under Disitamab Vedotin (RC48) in HR-positive/HER2-positive metastatic breast cancer with brain meningeal, and bone marrow involvement: A case report
IHC-P / Human
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