anti-DAO / D Amino Acid Oxidase antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG57940
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes DAO / D Amino Acid Oxidase |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | DAO / D Amino Acid Oxidase |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 1-347 of Human DAO (NP_001908.3). |
| 偶联标记 | Un-conjugated |
| 別名 | EC 1.4.3.3; D-amino-acid oxidase; DAO; DAMOX; OXDA; DAAO |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | Raji | ||||||
| 实际分子量 | 36 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | DAO |
| 全名 | D-amino-acid oxidase |
| 背景介绍 | This gene encodes the peroxisomal enzyme D-amino acid oxidase. The enzyme is a flavoprotein which uses flavin adenine dinucleotide (FAD) as its prosthetic group. Its substrates include a wide variety of D-amino acids, but it is inactive on the naturally occurring L-amino acids. Its biological function is not known; it may act as a detoxifying agent which removes D-amino acids that accumulate during aging. In mice, it degrades D-serine, a co-agonist of the NMDA receptor. This gene may play a role in the pathophysiology of schizophrenia. [provided by RefSeq, Jul 2008] |
| 生物功能 | Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids. [UniProt] |
| 细胞定位 | Peroxisome. [UniProt] |
| 预测分子量 | 39 kDa |
检测图片 (2)
ARG57940 anti-DAO / D Amino Acid Oxidase antibody ICC/IF image
Immunofluorescence: MCF-7 cells stained with ARG57940 anti-DAO / D Amino Acid Oxidase antibody.
ARG57940 anti-DAO / D Amino Acid Oxidase antibody WB image
Western blot: 25 µg of Raji cell lysate stained with ARG57940 anti-DAO / D Amino Acid Oxidase antibody at 1:1000 dilution.
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