anti-DAPK2 antibody

Key features and details

  • 产品描述: Goat Polyclonal antibody recognizes DAPK2
  • 反应物种: Hu, Ms
  • 预测物种: Dog, Rat, Pig
  • 应用: IHC-P, WB
  • 宿主: Goat
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: DAPK2
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG63157
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Product Details
概述
产品描述Goat Polyclonal antibody recognizes DAPK2
反应物种Hu, Ms
预测物种Dog, Rat, Pig
应用IHC-P, WB
宿主Goat
克隆Polyclonal
同位型IgG
靶点名称DAPK2
抗原物种Human
抗原C-KALHPRRRSSTS
偶联标记Un-conjugated
別名DRP1; DAP-kinase-related protein 1; DRP-1; DAP kinase 2; EC 2.7.11.1; Death-associated protein kinase 2
应用说明
应用建议
应用推荐稀释比
IHC-P2.5 µg/ml
WB1 - 3 µg/ml
应用说明WB: Recommend incubate at RT for 1h.
IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 13143 Mouse DAPK2

GeneID: 23604 Human DAPK2

Swiss-port # Q8VDF3 Mouse Death-associated protein kinase 2

Swiss-port # Q9UIK4 Human Death-associated protein kinase 2

背景介绍This gene encodes a protein that belongs to the serine/threonine protein kinase family. This protein contains a N-terminal protein kinase domain followed by a conserved calmodulin-binding domain with significant similarity to that of death-associated protein kinase 1 (DAPK1), a positive regulator of programmed cell death. Overexpression of this gene was shown to induce cell apoptosis. It uses multiple polyadenylation sites. [provided by RefSeq, Jul 2008]
研究领域Cell Biology and Cellular Response antibody; Cell Death antibody
预测分子量43 kDa
翻译后修饰Autophosphorylation at Ser-318 inhibits its catalytic activity. Dephosphorylated at Ser-318 in response to activated Fas and TNF-alpha receptors.
检测图片 (3)
  • ARG63157 anti-DAPK2 antibody WB image

    Western Blot: mouse brain extracts (RIPA buffer, 35 µg total protein per lane) stained with ARG63157 anti-DAPK2 antibody at 2 µg/ml dilution.

  • ARG63157 anti-DAPK2 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human thyroid tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG63157 anti-DAPK2 antibody at 2.5 µg/ml dilution followed by AP-staining.

  • ARG63157 anti-DAPK2 antibody IHC-P image

    Immunohistochemistry: paraffin embedded Human Breast. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG63157 anti-DAPK2 antibody at 2.5 µg/ml dilution followed by AP-staining.

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