anti-Dclre1c / Artemis antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes Dclre1c / Artemis
  • 反应物种: Hu
  • 应用: WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: Dclre1c / Artemis
  • 抗原物种: Human
  • 抗原: Synthetic peptide
  • Brand:
CAT.NO. : ARG44309
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes Dclre1c / Artemis
反应物种Hu
应用WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称Dclre1c / Artemis
抗原物种Human
抗原Synthetic peptide
偶联标记Un-conjugated
別名DCLRE1C; DNA Cross-Link Repair 1C; SNM1C; ARTEMIS; A-SCID; SCIDA
应用说明
应用建议
应用推荐稀释比
WB1:500-1:1000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Antigen Affinity Purified
缓冲液PBS with 0.02% Sodium azide
抗菌剂0.02% Sodium azide
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
生物信息
数据库连接

GeneID: 64421 Human DCLRE1C

Swiss-port # Q96SD1 Human Protein artemis

基因名称DCLRE1C
全名DNA Cross-Link Repair 1C
背景介绍This gene encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The encoded protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins. The protein also functions in the regulation of the cell cycle in response to DNA damage. Mutations in this gene can cause Athabascan-type severe combined immunodeficiency (SCIDA) and Omenn syndrome. Alternative splicing results in multiple transcript variants.
生物功能Nuclease involved in DNA non-homologous end joining (NHEJ); required for double-strand break repair and V(D)J recombination.
细胞定位Nucleus
预测分子量78 kDa
翻译后修饰Phosphoprotein
检测图片 (1)
  • ARG44309 anti-Dclre1c / Artemis antibody WB image

    Western blot: Human testis lysate stained with ARG44309 anti-Dclre1c / Artemis antibody.

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