anti-DDOST antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes DDOST
  • 反应物种: Hu, Ms, Rat
  • 应用: IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: DDOST
  • 抗原物种: Human
  • 抗原: Recombinant fusion protein corresponding to aa. 40-300 of Human DDOST (NP_005207.2).
  • Brand:
CAT.NO. : ARG58482
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes DDOST
反应物种Hu, Ms, Rat
应用IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称DDOST
抗原物种Human
抗原Recombinant fusion protein corresponding to aa. 40-300 of Human DDOST (NP_005207.2).
偶联标记Un-conjugated
別名Oligosaccharyl transferase 48 kDa subunit; CDG1R; OST48; OKSWcl45; EC 2.4.99.18; Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; OST; AGER1; DDOST 48 kDa subunit; WBP1
应用说明
应用建议
应用推荐稀释比
IHC-P1:50 - 1:200
WB1:500 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照U-87MG
实际分子量51 kDa
属性
形式Liquid
纯化Affinity purified.
缓冲液PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 13200 Mouse DDOST

GeneID: 1650 Human DDOST

GeneID: 313648 Rat DDOST

基因名称DDOST
全名dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
背景介绍This gene encodes a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. The product of this gene is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia. [provided by RefSeq, Jul 2008]
生物功能Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. [UniProt]
细胞定位Endoplasmic reticulum membrane, Single-pass type I membrane protein,. [UniProt]
预测分子量51 kDa
检测图片 (1)
  • ARG58482 anti-DDOST antibody WB image

    Western blot: 25 µg of U-87MG cell lysate stained with ARG58482 anti-DDOST antibody at 1:1000 dilution.

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