anti-DHRS2 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG58094
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes DHRS2 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | DHRS2 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 1-300 of Human DHRS2 (NP_878912.1). |
| 偶联标记 | Un-conjugated |
| 別名 | HEP27; Protein D; Dicarbonyl reductase HEP27; EC 1.1.1.-; Dehydrogenase/reductase SDR family member 2, mitochondrial; SDR25C1; Short chain dehydrogenase/reductase family 25C member 1 |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | MCF7 | ||||||
| 实际分子量 | ~ 33 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q13268 Human Dehydrogenase/reductase SDR family member 2, mitochondrial |
|---|---|
| 基因名称 | DHRS2 |
| 全名 | dehydrogenase/reductase (SDR family) member 2 |
| 生物功能 | Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3,4-Hexanedione, 2,3-Heptanedione and 1-Phenyl-1,2-propanedione as substrates. No reductase activity is displayed in vitro with steroids, retinoids and sugars as substrates. Attenuates MDM2-mediated p53/TP53 degradation, leading to p53/TP53 stabilization and increased transcription activity, resulting in the accumulation of MDM2 and CDKN1A/p21. [UniProt] |
| 细胞定位 | Mitochondrion matrix, Nucleus. [UniProt] |
| 预测分子量 | 30 kDa |
检测图片 (2)
ARG58094 anti-DHRS2 antibody ICC/IF image
Immunofluorescence: HeLa cells stained with ARG58094 anti-DHRS2 antibody.
ARG58094 anti-DHRS2 antibody WB image
Western blot: 25 µg of MCF7 cell lysate stained with ARG58094 anti-DHRS2 antibody at 1:1000 dilution.
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