anti-DIAPH1 antibody
Key features and details
- 产品描述:
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- 预测物种:
- 应用:
- 特异性:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
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Brand:
CAT.NO. : ARG65142
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Product Details
概述
| 产品描述 | Goat Polyclonal antibody recognizes DIAPH1 |
|---|---|
| 反应物种 | Ms |
| 预测物种 | Hu |
| 应用 | WB |
| 特异性 | This antibody is expected to recognize both reported isoforms (NP_005210.3; NP_001073280.1). |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | DIAPH1 |
| 抗原物种 | Human |
| 抗原 | C-QTKTSKAKKDQ |
| 偶联标记 | Un-conjugated |
| 別名 | DRF1; Diaphanous-related formin-1; LFHL1; DFNA1; Protein diaphanous homolog 1; hDIA1; DIA1 |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 背景介绍 | This gene is a homolog of the Drosophila diaphanous gene, and has been linked to autosomal dominant, fully penetrant, nonsyndromic sensorineural progressive low-frequency hearing loss. Actin polymerization involves proteins known to interact with diaphanous protein in Drosophila and mouse. It has therefore been speculated that this gene may have a role in the regulation of actin polymerization in hair cells of the inner ear. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
|---|---|
| 研究领域 | Signaling Transduction antibody |
| 预测分子量 | 141 kDa |
| 翻译后修饰 | Phosphorylation at Thr-768 is stimulated by cAMP and regulates stability, complex formation and mitochondrial movement. |
检测图片 (1)
ARG65142 anti-DIAPH1 antibody WB image
Western Blot: NIH3T3 lysate (35 µg protein in RIPA buffer) stained with ARG65142 anti-DIAPH1 antibody at 0.3 µg/ml dilution.
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