anti-DNAJC19 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG41019
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes DNAJC19 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | DNAJC19 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 1-116 of Human DNAJC19 (NP_660304.1). |
| 偶联标记 | Un-conjugated |
| 別名 | TIM14; TIMM14; PAM18; Mitochondrial import inner membrane translocase subunit TIM14; DnaJ homolog subfamily C member 19 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | HT1080 | ||||||
| 实际分子量 | 12 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q96DA6 Human Mitochondrial import inner membrane translocase subunit TIM14 Swiss-port # Q9CQV7 Mouse Mitochondrial import inner membrane translocase subunit TIM14 |
|---|---|
| 基因名称 | DNAJC19 |
| 全名 | DnaJ (Hsp40) homolog, subfamily C, member 19 |
| 背景介绍 | The protein encoded by this gene is thought to be part of a complex involved in the ATP-dependent transport of transit peptide-containing proteins from the inner cell membrane to the mitochondrial matrix. Defects in this gene are a cause of 3-methylglutaconic aciduria type 5 (MGA5), also known as dilated cardiomyopathy with ataxia (DCMA). Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1, 2, 6, 10, 14 and 19. [provided by RefSeq, Jan 2012] |
| 生物功能 | Probable component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. May act as a co-chaperone that stimulate the ATP-dependent activity (By similarity). [UniProt] |
| 细胞定位 | Mitochondrion inner membrane; Single-pass membrane protein. [UniProt] |
| 预测分子量 | 12 kDa |
检测图片 (2)
ARG41019 anti-DNAJC19 antibody ICC/IF image
Immunofluorescence: HeLa cells stained with ARG41019 anti-DNAJC19 antibody at 1:100 dilution.
ARG41019 anti-DNAJC19 antibody WB image
Western blot: 25 µg of HT1080 cell lysate stained with ARG41019 anti-DNAJC19 antibody at 1:3000 dilution through one-step method.
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