anti-Dopamine beta Hydroxylase antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG52262
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Product Details
概述
| 产品描述 | Sheep Polyclonal antibody recognizes Dopamine beta Hydroxylase |
|---|---|
| 反应物种 | Hu, NHuPrm |
| 应用 | WB |
| 宿主 | Sheep |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Dopamine beta Hydroxylase |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH |
| 偶联标记 | Un-conjugated |
| 別名 | EC 1.14.17.1; DBM; Dopamine beta-monooxygenase; Dopamine beta-hydroxylase |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | Specific for the ~75k DBH protein in Western blots * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity Purified |
| 缓冲液 | 10 mM HEPES (pH 7.5), 150 mM NaCl, 0.1 mg/ml BSA and 50% Glycerol |
| 稳定剂 | 0.1 mg/ml BSA, 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | DBH |
| 全名 | dopamine beta-hydroxylase (dopamine beta-monooxygenase) |
| 背景介绍 | DBH catalyzes the conversion of dopamine to norepinephrine and serves as a marker of noradrenergic cells. DBH antibodies and antibodies for other markers of catecholamine biosynthesis are widely used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson’s disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999). The expression of DBH is also elevated during stress (Sabban and Kvetnansky, 2001). |
| 研究领域 | Cancer antibody; Metabolism antibody; Neuroscience antibody |
| 预测分子量 | 69 kDa |
| 翻译后修饰 | N-glycosylated. Proteolytic cleavage after the membrane-anchor leads to the release of the soluble form. |
检测图片 (1)
ARG52262 anti-Dopamine beta Hydroxylase antibody WB image
Western Blot: 20 ug of human adrenal medulla lysate showing specific immunolabeling of the ~75k DBH protein stained with Dopamine-Hydroxylase antibody (ARG52262).
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