anti-DRD1 / Dopamine Receptor D1 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes DRD1 / Dopamine Receptor D1
  • 反应物种: Hu, Ms, Rat
  • 应用: ICC/IF, IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: DRD1 / Dopamine Receptor D1
  • 抗原物种: Human
  • 抗原: Recombinant protein of Human DRD1 / Dopamine Receptor D1.
  • Brand:
CAT.NO. : ARG43269
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes DRD1 / Dopamine Receptor D1
反应物种Hu, Ms, Rat
应用ICC/IF, IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称DRD1 / Dopamine Receptor D1
抗原物种Human
抗原Recombinant protein of Human DRD1 / Dopamine Receptor D1.
偶联标记Un-conjugated
別名DADR; DRD1A; D(1A) dopamine receptor; Dopamine D1 receptor
应用说明
应用建议
应用推荐稀释比
ICC/IF1:100 - 1:500
IHC-P1:50 - 1:200
WB1:500 - 1:1000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照Mouse kidney
实际分子量~ 74 kDa
属性
形式Liquid
纯化Purification with Protein A.
缓冲液PBS (pH 7.2), 0.02% Sodium azide and 50% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 13488 Mouse DRD1

GeneID: 1812 Human DRD1

Swiss-port # P21728 Human D(1A) dopamine receptor

Swiss-port # Q61616 Mouse D(1A) dopamine receptor

基因名称DRD1
全名dopamine receptor D1
背景介绍This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene. [provided by RefSeq, Jul 2008]
生物功能Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase. [UniProt]
细胞定位Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Transport from the endoplasmic reticulum to the cell surface is regulated by interaction with DNAJC14. [UniProt]
预测分子量49 kDa
检测图片 (6)
  • ARG43269 anti-DRD1 / Dopamine Receptor D1 antibody ICC/IF image

    Immunofluorescence: 293T cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. Cells were stained with ARG43269 anti-DRD1 / Dopamine Receptor D1 antibody (red). DAPI (blue) for nuclear staining.

  • ARG43269 anti-DRD1 / Dopamine Receptor D1 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Mouse brain tissue stained with ARG43269 anti-DRD1 / Dopamine Receptor D1 antibody. Counter stained with hematoxylin.

  • ARG43269 anti-DRD1 / Dopamine Receptor D1 antibody WB image

    Western blot: Mouse kidney lysate stained with ARG43269 anti-DRD1 / Dopamine Receptor D1 antibody at 1:500 dilution.

  • ARG43269 anti-DRD1 / Dopamine Receptor D1 antibody ICC/IF image

    Immunofluorescence: Neuro-2a cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. Cells were stained with ARG43269 anti-DRD1 / Dopamine Receptor D1 antibody (red). DAPI (blue) for nuclear staining.

  • ARG43269 anti-DRD1 / Dopamine Receptor D1 antibody ICC/IF image

    Immunofluorescence: SH-SY5Y cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. Cells were stained with ARG43269 anti-DRD1 / Dopamine Receptor D1 antibody (red). DAPI (blue) for nuclear staining.

  • ARG43269 anti-DRD1 / Dopamine Receptor D1 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Rat brain tissue stained with ARG43269 anti-DRD1 / Dopamine Receptor D1 antibody. Counter stained with hematoxylin.

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