anti-DRD2 / Dopamine Receptor D2 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 特异性:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
CAT.NO. : ARG11043
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes DRD2 / Dopamine Receptor D2 |
|---|---|
| 反应物种 | Hu, Rat |
| 应用 | ELISA, ICC/IF, IHC-P, IP, WB |
| 特异性 | The antibody has no cross reactivity to D1 receptor (9% homology), D3 receptor (18% homology), D4 receptor (27% homology) and D5 receptor (9% homology). |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | DRD2 / Dopamine Receptor D2 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide from Human Dopamine D2 receptor. |
| 偶联标记 | Un-conjugated |
| 別名 | D2R; D2DR; D(2) dopamine receptor; Dopamine D2 receptor |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | Tris-Glycine Buffer (pH 7.4 - 7.8), Hepes, cryo-protective agents, 0.02% Sodium azide, 30% Glycerol and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 30% Glycerol and 0.5% BSA |
| 浓度 | 0.55 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | DRD2 |
| 全名 | dopamine receptor D2 |
| 背景介绍 | This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing. [provided by RefSeq, Jul 2008] |
| 生物功能 | Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. [UniProt] |
| 细胞定位 | Cell membrane; Multi-pass membrane protein [UniProt] |
| 预测分子量 | 51 kDa |
检测图片 (1)
ARG11043 anti-DRD2 / Dopamine Receptor D2 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Rat brain stained with ARG11043 anti-DRD2 / Dopamine Receptor D2 antibody at 1:100 dilution. (20X magnification).
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