anti-DsbA-L antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes DsbA-L
  • 反应物种: Hu, Ms
  • 应用: IHC, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: DsbA-L
  • 抗原物种: Mouse
  • 抗原: Full length recombinant mouse DsbA-L protein
  • Brand:
CAT.NO. : ARG52267
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes DsbA-L
反应物种Hu, Ms
应用IHC, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称DsbA-L
抗原物种Mouse
抗原Full length recombinant mouse DsbA-L protein
偶联标记Un-conjugated
別名Glutathione S-transferase kappa 1; hGSTK1; GST; GST class-kappa; GST13-13; EC 2.5.1.18; Glutathione S-transferase subunit 13; GST13; GST 13-13; GSTK1-1
应用说明
应用建议
应用推荐稀释比
IHC1:200
WB1:2000
应用说明Specific for the ~25 kDa DsbA-L protein in Western blots of 3T3-L1 adipocytes and mouse white and brown adipose tissue lysate samples. It is suggested that you add 1% BSA to the antibody dilution buffer.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Serum
缓冲液Serum and 40 % Glycerol
稳定剂40 % Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 373156 Human GSTK1

GeneID: 76263 Mouse GSTK1

Swiss-port # Q9DCM2 Mouse Glutathione S-transferase kappa 1

Swiss-port # Q9Y2Q3 Human Glutathione S-transferase kappa 1

基因名称Gstk1
全名glutathione S-transferase kappa 1
背景介绍Disulfide-bond-A oxidoreductase-like protein (DsbA-L, previously named as GST Kappa) is an adiponectin-interacting protein. DsbA-L is highly expressed in adipose tissue, and its expression level is negatively correlated with obesity in mice and humans. DsbA-L expression in 3T3-L1 adipocytes is stimulated by the insulin sensitizer rosiglitazone and inhibited by the inflammatory cytokine TNFalpha. Polymorphism of DsbA-L gene has recently been implicated in insulin secretion and body fat distribution (Gao F et al., 2009). Overexpression of DsbA-L promotes adiponectin multimerization while suppressing DsbA-L expression by RNAi markedly and selectively reduces adiponectin levels and secretion in 3T3-L1 adipocytes. Recent studies identify DsbA-L as a key regulator for adiponectin biosynthesis (Liu et al., 2008).
研究领域Cell Biology and Cellular Response antibody; Controls and Markers antibody; Metabolism antibody; Signaling Transduction antibody
预测分子量25 kDa
检测图片 (1)
  • ARG52267 anti-DsbA-L antibody WB image

    Western Blot: mouse adipose tissue showing specific immunolabeling of the ~25k DsbA-L protein stained with DsbA-L antibody (ARG52267).

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