anti-DTNA / alpha dystrobrevin antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG58501
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes DTNA / alpha dystrobrevin |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | DTNA / alpha dystrobrevin |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 240-480 of Human DTNA / alpha dystrobrevin (NP_001381.2). |
| 偶联标记 | Un-conjugated |
| 別名 | D18S892E; DTN; DRP3; Dystrobrevin alpha; Alpha-dystrobrevin; LVNC1; Dystrophin-related protein 3; DTN-A |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | Mouse brain | ||||
| 实际分子量 | ~ 80 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | DTNA |
| 全名 | dystrobrevin, alpha |
| 背景介绍 | The protein encoded by this gene belongs to the dystrobrevin subfamily of the dystrophin family. This protein is a component of the dystrophin-associated protein complex (DPC), which consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and alpha- and beta-dystrobrevin. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Mutations in this gene are associated with left ventricular noncompaction with congenital heart defects. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] |
| 生物功能 | May be involved in the formation and stability of synapses as well as being involved in the clustering of nicotinic acetylcholine receptors. [UniProt] |
| 细胞定位 | Cytoplasm, Cell junction, synapse, Cell membrane. [UniProt] |
| 预测分子量 | 84 kDa |
| 翻译后修饰 | Phosphorylation of DTN-1 on tyrosine kinase substrate domain present in the C-terminus. [UniProt] |
检测图片 (1)
ARG58501 anti-DTNA / alpha dystrobrevin antibody WB image
Western blot: 25 µg of Mouse brain lysate stained with ARG58501 anti-DTNA / alpha dystrobrevin antibody at 1:3000 dilution.
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