anti-DTX2 / Deltex2 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG59961
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes DTX2 / Deltex2 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | DTX2 / Deltex2 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 1-280 of Human DTX2 (NP_065943.2). |
| 偶联标记 | Un-conjugated |
| 別名 | RNF58; EC 6.3.2.-; Probable E3 ubiquitin-protein ligase DTX2; RING finger protein 58; Protein deltex-2; Deltex2; hDTX2 |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | Mouse testis and HepG2 | ||||||
| 实际分子量 | 67 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q86UW9 Human Probable E3 ubiquitin-protein ligase DTX2 Swiss-port # Q8R3P2 Mouse Probable E3 ubiquitin-protein ligase DTX2 |
|---|---|
| 基因名称 | DTX2 |
| 全名 | deltex 2, E3 ubiquitin ligase |
| 背景介绍 | DTX2 functions as an E3 ubiquitin ligase (Takeyama et al., 2003 [PubMed 12670957]).[supplied by OMIM, Nov 2009] |
| 生物功能 | Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as a ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity. [UniProt] |
| 细胞定位 | Cytoplasm. Nucleus. Note=Predominantly cytoplasmic. Partially nuclear. [UniProt] |
| 预测分子量 | 67 kDa |
检测图片 (3)
ARG59961 anti-DTX2 / Deltex2 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human kidney stained with ARG59961 anti-DTX2 / Deltex2 antibody at 1:100 dilution.
ARG59961 anti-DTX2 / Deltex2 antibody WB image
Western blot: 25 µg of Mouse testis and HepG2 cell lysates stained with ARG59961 anti-DTX2 / Deltex2 antibody at 1:1000 dilution.
ARG59961 anti-DTX2 / Deltex2 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Mouse liver stained with ARG59961 anti-DTX2 / Deltex2 antibody at 1:100 dilution.
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