anti-DUX4 antibody [P2B1]
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Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 特异性:
- 宿主:
- 克隆:
- 克隆号:
- 同位型:
- 靶点名称:
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Brand:
CAT.NO. : ARG20542
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Product Details
概述
| 产品描述 | Mouse Monoclonal antibody [P2B1] recognizes DUX4 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | ICC/IF, IHC, WB |
| 特异性 | This antibody recognizes human DUX4. Iut does not cross react with DUX4c. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | P2B1 |
| 同位型 | IgG1 |
| 靶点名称 | DUX4 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide around 76 aa (C-terminus) of Human DUX4 with glutathione-s-transferase (gst) tag. |
| 偶联标记 | Un-conjugated |
| 別名 | DUX4; DUX10 |
应用说明
| 应用建议 |
| ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS (pH 7.4), 50% Glycerol and 0.09% Sodium azide |
| 抗菌剂 | 0.09% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | DUX4L1 |
| 全名 | double homeobox 4 like 1 |
| 背景介绍 | DUX4, or double homeobox4, is a human protein that is a transcriptional activator of paired-like homeodomain transcription factor 1. Clinically it is a facioscapulohumeral muscular dystrophy candidate gene that appears to have a toxic gain of function. In FSHD individuals, the expression of the full-length DUX4 transcript is not completely suppressed in skeletal muscle and possibly other differentiated tissues. |
| 细胞定位 | Nuclear |
| 产品亮点 | Related products: anti-DUX4 antibody [P2B1] |
| 研究领域 | Developmental Biology antibody |
| 预测分子量 | 45 kDa |
检测图片 (2)
ARG20542 anti-DUX4 antibody [P2B1] ICC/IF image
Immunofluorescence: C2C12 myoblasts transfected with pCS2+DUX4, stained with ARG20542 anti-DUX4 antibody [P2B1]. Counter-stained with DAPI for nuclei.
ARG20542 anti-DUX4 antibody [P2B1] WB image
Western blot: C2C12 cells transfected with pCS2+DUX4 which contains an additional upstream start site, stained with ARG20542 anti-DUX4 antibody [P2B1].
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