anti-EDAR antibody [19E8]

CAT.NO. : ARG57039

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Size:

50 μl

*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	Mouse Monoclonal antibody [19E8] recognizes EDAR
反应物种	Hu
应用	FACS, WB
宿主	Mouse
克隆	Monoclonal
克隆号	19E8
同位型	IgG2a, kappa
靶点名称	EDAR
抗原物种	Human
抗原	Recombinant fragment around aa. 27-448 of Human EDAR.
偶联标记	Un-conjugated
別名	ECTD10B; Ectodermal dysplasia receptor; DL; ECTD10A; EDA1R; Tumor necrosis factor receptor superfamily member EDAR; ED1R; Downless homolog; Ectodysplasin-A receptor; ED5; HRM1; ED3; EDA3; Anhidrotic ectodysplasin receptor 1; EDA-A1R; EDA-A1 receptor

应用说明

应用建议

应用	推荐稀释比
FACS	Assay-dependent
WB	1:1000

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purification with Protein A.
缓冲液	PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	10% Glycerol
浓度	1 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 10913 Human EDAR Swiss-port # Q9UNE0 Human Tumor necrosis factor receptor superfamily member EDAR
基因名称	EDAR
全名	ectodysplasin A receptor
背景介绍	This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia. [provided by RefSeq, Jul 2008]
生物功能	Receptor for EDA isoform A1, but not for EDA isoform A2. Mediates the activation of NF-kappa-B and JNK. May promote caspase-independent cell death. [UniProt]
预测分子量	49 kDa

检测图片 (2)

ARG57039 anti-EDAR antibody [19E8] FACS image
Flow Cytometry: HeLa cell line stained with ARG57039 anti-EDAR antibody [19E8] at 2-5 µg for 1x10^6 cells (red line). Secondary antibody: Goat anti-Mouse IgG Alexa fluor 488 conjugate. Isotype control antibody was Mouse IgG (black line).
ARG57039 anti-EDAR antibody [19E8] WB image
Western blot: 1) 50 ng of Recombinant protein, 2) 40 µg of A549 cell lysate, 3) 40 µg of Ramos cell lysate stained with ARG57039 anti-EDAR antibody [19E8] at 1:1000.

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