anti-EML4 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes EML4
  • 反应物种: Hu, Ms, Rat
  • 应用: ICC/IF, IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: EML4
  • 抗原物种: Human
  • 抗原: Recombinant fusion protein corresponding to aa. 360-560 of Human EML4 (NP_061936.2).
  • Brand:
CAT.NO. : ARG43031
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes EML4
反应物种Hu, Ms, Rat
应用ICC/IF, IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称EML4
抗原物种Human
抗原Recombinant fusion protein corresponding to aa. 360-560 of Human EML4 (NP_061936.2).
偶联标记Un-conjugated
別名ELP120; ROPP120; C2orf2; Echinoderm microtubule-associated protein-like 4; EMAP-4; Ropp 120; EMAPL4; Restrictedly overexpressed proliferation-associated protein
应用说明
应用建议
应用推荐稀释比
ICC/IF1:50 - 1:200
IHC-P1:50 - 1:200
WB1:500 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照HepG2
属性
形式Liquid
纯化Affinity purified.
缓冲液PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 27436 Human EML4

GeneID: 78798 Mouse EML4

Swiss-port # Q3UMY5 Mouse Echinoderm microtubule-associated protein-like 4

Swiss-port # Q9HC35 Human Echinoderm microtubule-associated protein-like 4

基因名称EML4
全名echinoderm microtubule associated protein like 4
背景介绍This gene is a member of the echinoderm microtubule associated protein-like family. The encoded WD-repeat protein may be involved in microtubule formation. Abnormal fusion of parts of this gene with portions of the anaplastic lymphoma receptor tyrosine kinase gene, which generates EML4-ALK fusion transcripts, is one of the primary mutations associated with non-small cell lung cancer. Alternative splicing of this gene results in two transcript variants. [provided by RefSeq, Jan 2015]
生物功能May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic. [UniProt]
细胞定位Cytoplasm, cytoskeleton. [UniProt]
预测分子量109 kDa
检测图片 (3)
  • ARG43031 anti-EML4 antibody ICC/IF image

    Immunofluorescence: L929 cells stained with ARG43031 anti-EML4 antibody at 1:100 dilution.

  • ARG43031 anti-EML4 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Rat kidney tissue stained with ARG43031 anti-EML4 antibody at 1:100 dilution.

  • ARG43031 anti-EML4 antibody WB image

    Western blot: 25 µg of HepG2 cell lysate stained with ARG43031 anti-EML4 antibody at 1:1000 dilution.

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