anti-ENOX2 antibody
CAT.NO. : ARG57949
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概述
产品描述 | Rabbit Polyclonal antibody recognizes ENOX2 |
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反应物种 | Hu, Ms, Rat |
应用 | ICC/IF, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | ENOX2 |
抗原物种 | Human |
抗原 | Recombinant fusion protein corresponding to aa. 411-610 of Human ENOX2 (NP_872114.1). |
偶联标记 | Un-conjugated |
別名 | APK1; EC 1.-.-.-; APK1 antigen; Ecto-NOX disulfide-thiol exchanger 2; COVA1; Tumor-associated hydroquinone oxidase; Cytosolic ovarian carcinoma antigen 1; tNOX |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
阳性对照 | THP-1 | ||||||
实际分子量 | ~ 65 kDa |
属性
形式 | Liquid |
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纯化 | Affinity purified. |
缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 50% Glycerol |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # Q16206 Human Ecto-NOX disulfide-thiol exchanger 2 Swiss-port # Q8R0Z2 Mouse Ecto-NOX disulfide-thiol exchanger 2 |
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基因名称 | ENOX2 |
全名 | ecto-NOX disulfide-thiol exchanger 2 |
背景介绍 | This gene is a tumor-specific member of the ECTO-NOX family of genes that encode cell surface NADH oxidases. The encoded protein has two enzymatic activities: catalysis of hydroquinone or NADH oxidation, and protein disulfide interchange. The protein also displays prion-like properties. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] |
生物功能 | May be involved in cell growth. Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a protein disulfide-thiol interchange/oxidoreductase activity which may control physical membrane displacements associated with vesicle budding or cell enlargement. The activities oscillate with a period length of 22 minutes and play a role in control of the ultradian cellular biological clock. [UniProt] |
细胞定位 | Cell membrane, Secreted, extracellular space. [UniProt] |
预测分子量 | 70 kDa |
翻译后修饰 | Glycosylated. [UniProt] |
