anti-Eotaxin antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG59966
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Eotaxin |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Eotaxin |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 1-97 of Human Eotaxin (NP_002977.1). |
| 偶联标记 | Un-conjugated |
| 別名 | SCYA11; C-C motif chemokine 11; Eosinophil chemotactic protein; Eotaxin; Small-inducible cytokine A11 |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | 20 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CCL11 |
| 全名 | chemokine (C-C motif) ligand 11 |
| 背景介绍 | This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil-specific chemokine is thought to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. [provided by RefSeq, Sep 2014] |
| 生物功能 | In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3. [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
| 预测分子量 | 11 kDa |
| 翻译后修饰 | O-linked glycan consists of a Gal-GalNAc disaccharide which is modified with up to 2 sialic acid residues. [UniProt] |
检测图片 (1)
ARG59966 anti-Eotaxin antibody ICC/IF image
Immunofluorescence: A549 cells stained with ARG59966 anti-Eotaxin antibody.
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