anti-ERCC1 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG54172
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Product Details
概述
| 产品描述 | Mouse Monoclonal antibody recognizes ERCC1 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG2b |
| 靶点名称 | ERCC1 |
| 抗原物种 | Human |
| 抗原 | Purified recombinant human ERCC1 protein fragments expressed in E.coli. |
| 偶联标记 | Un-conjugated |
| 別名 | DNA excision repair protein ERCC-1; RAD10; COFS4; UV20 |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 实际分子量 | 39 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | PBS (pH 7.4), 0.02% Sodium azide, 0.1mg/ml BSA and 50% Glycerol |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.1mg/ml BSA, 50% Glycerol |
| 浓度 | 18 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # P07992 Human DNA excision repair protein ERCC-1 |
|---|---|
| 基因名称 | ERCC1 |
| 全名 | excision repair cross-complementation group 1 |
| 背景介绍 | Isoform 1:Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair.Responsible,in conjunction with SLX4,for the first step in the repair of interstrand cross-links (ICL).Participates in the processing of anaphase bridge-generating DNA structures,which consist in incompletely processed DNA lesions arising during S or G2 phase,and can result in cytokinesis failure.Also required for homology-directed repair (HDR) of DNA double-strand breaks,in conjunction with SLX4. |
| 生物功能 | Isoform 1: Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4. [UniProt] |
| 细胞定位 | Isoform 1: Nucleus. Isoform 2: Cytoplasm. Nucleus. Isoform 3: Nucleus. Isoform 4: Nucleus. |
| 研究领域 | Cancer antibody; Gene Regulation antibody |
| 预测分子量 | 33 kDa |
检测图片 (1)
ARG54172 anti-ERCC1 antibody WB image
Western blot: T47D cell lysate stained with ARG54172 anti-ERCC1 antibody at 1:1000 dilution.
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