anti-EVI1 / AML1 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 特异性:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
CAT.NO. : ARG65147
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Product Details
概述
| 产品描述 | Goat Polyclonal antibody recognizes EVI1 / AML1 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 特异性 | This antibody is expected to recognize all reported isoforms (NP_001098547.3; NP_005232.2; NP_004982.2; NP_001157471.1; NP_001157472.1). Reported variants represent identical protein: NP_001098548.2, NP_005232.2 |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | EVI1 / AML1 |
| 抗原物种 | Human |
| 抗原 | C-DKESLHSTSH |
| 偶联标记 | Un-conjugated |
| 別名 | MDS1 and EVI1 complex locus protein EVI1; AML1-EVI-1; Ecotropic virus integration site 1 protein homolog; EVI1; MDS1-EVI1; PRDM3; MDS1; EVI-1 |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q03112 Human MDS1 and EVI1 complex locus protein EVI1 |
|---|---|
| 背景介绍 | The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Mar 2011] |
| 研究领域 | Gene Regulation antibody |
| 预测分子量 | 138 kDa |
| 翻译后修饰 | Phosphorylated. May be acetylated by CREBBP and KAT2B. |
检测图片 (1)
ARG65147 anti-EVI1 / AML1 antibody WB image
Western Blot: A549 lysate (35 µg protein in RIPA buffer) stained with ARG65147 anti-EVI1 antibody at 2 µg/ml dilution.
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