anti-EXOC3 / rSec6 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes EXOC3 / rSec6
  • 反应物种: Hu, Ms, Rat
  • 应用: ICC/IF, IHC-P, IP, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: EXOC3 / rSec6
  • 抗原物种: Human
  • 抗原: Synthetic peptide of Human EXOC3 / rSec6.
  • Brand:
CAT.NO. : ARG42880
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes EXOC3 / rSec6
反应物种Hu, Ms, Rat
应用ICC/IF, IHC-P, IP, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称EXOC3 / rSec6
抗原物种Human
抗原Synthetic peptide of Human EXOC3 / rSec6.
偶联标记Un-conjugated
別名SEC6L1; Exocyst complex component Sec6; Sec6p; Exocyst complex component 3; SEC6
应用说明
应用建议
应用推荐稀释比
ICC/IF1:20 - 1:50
IHC-P1:20 - 1:100
IP1:20 - 1:50
WB1:1000 - 1:5000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照NIH/3T3
实际分子量~ 85 kDa
属性
形式Liquid
纯化Affinity purified.
缓冲液50 mM Tris-Glycine (pH 7.4), 150 mM NaCl, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA.
抗菌剂0.01% Sodium azide
稳定剂40% Glycerol and 0.05% BSA
浓度Batch dependent
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 11336 Human EXOC3

GeneID: 211446 Mouse EXOC3

GeneID: 252881 Rat EXOC3

基因名称EXOC3
全名exocyst complex component 3
背景介绍The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. [provided by RefSeq, Jul 2008]
生物功能Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. [UniProt]
细胞定位Cytoplasm. Cytoplasm, perinuclear region. Cell projection, growth cone. Midbody. Golgi apparatus. Note=Perinuclear in undifferentiated cells. Redistributes to growing neurites and growth cones during neuronal differentiation (By similarity). During mitosis, early recruitment to the midbody requires RALA, but not RALB, and EXOC2. In late stages of cytokinesis, localization to the midbody is RALB-dependent (PubMed:18756269). [UniProt]
预测分子量86 kDa
检测图片 (1)
  • ARG42880 anti-EXOC3 / rSec6 antibody WB image

    Western blot: NIH/3T3 cell lysate stained with ARG42880 anti-EXOC3 / rSec6 antibody at 1:1000 dilution.

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