anti-EXOSC10 / Rrp6p antibody
CAT.NO. : ARG44826
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概述
产品描述 | Mouse Monoclonal antibody recognizes EXOSC10 / Rrp6p |
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反应物种 | Hu |
应用 | IHC-P, IP, WB |
宿主 | Mouse |
克隆 | Monoclonal |
同位型 | IgG1 |
靶点名称 | EXOSC10 / Rrp6p |
抗原物种 | Human |
抗原表位 | PFRMFLPSLG HRAPVSQAAK FDPSTKIYEI SNRWKLAQVQ VQKDSKEAVK KKAAEQTAAR EQAKEACKAA AEQAISVRQQ VVLENAAKKR ERATSDPRTT EQKQEKKRLK ISKKPKDPEP PEKEFTPYDY SQSDFKAFAG NSKSKVSSQF DPNKQTPSGK |
偶联标记 | Un-conjugated |
別名 | EXOSC10; Exosome Component 10; PM/Scl-100; RRP6; PM-Scl; PMSCL2; Rrp6p; P2; P3; P4; P100 Polymyositis-Scleroderma Overlap Syndrome-Associated Autoantigen; Polymyositis/Scleroderma Autoantigen 100 KDa; Polymyositis/Scleroderma Autoantigen 2; Exosome Complex Component 10; PMSCL; Polymyositis/Scleroderma Autoantigen 2 (100kD); Polymyositis/Scleroderma Autoantigen 2, 100kDa; Autoantigen PM/Scl 2; Autoantigen PM-SCL; EC 3.1.13.- |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Protein A purification |
缓冲液 | PBS with 0.09% sodium azide |
抗菌剂 | 0.09% sodium azide |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
基因名称 | EXOSC10 |
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全名 | Exosome Component 10 |
背景介绍 | Enables 3'-5'-exoribonuclease activity. Involved in several processes, including RNA catabolic process; maturation of 5.8S rRNA; and negative regulation of telomere maintenance via telomerase. Located in cytosol; nuclear lumen; and transcriptionally active chromatin. Part of nuclear exosome (RNase complex). [provided by Alliance of Genome Resources, Apr 2022] |
生物功能 | Regulates metabolism of C9orf72-derived repeat RNA that can be translated into toxic dipeptide repeat proteins. [UniProt] |
细胞定位 | Cytoplasm, Exosome, Nucleus. [UniProt] |
翻译后修饰 | Isopeptide bond, Phosphoprotein, Ubl conjugation. [UniProt] |
