anti-EXOSC10 / Rrp6p antibody

Key features and details

  • 产品描述: Mouse Monoclonal antibody recognizes EXOSC10 / Rrp6p
  • 反应物种: Hu
  • 应用: IHC-P, IP, WB
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 同位型: IgG1
  • 靶点名称: EXOSC10 / Rrp6p
  • 抗原物种: Human
  • 抗原表位: PFRMFLPSLG HRAPVSQAAK FDPSTKIYEI SNRWKLAQVQ VQKDSKEAVK KKAAEQTAAR EQAKEACKAA AEQAISVRQQ VVLENAAKKR ERATSDPRTT EQKQEKKRLK ISKKPKDPEP PEKEFTPYDY SQSDFKAFAG NSKSKVSSQF DPNKQTPSGK
  • Brand:
CAT.NO. : ARG44826
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Product Details
概述
产品描述Mouse Monoclonal antibody recognizes EXOSC10 / Rrp6p
反应物种Hu
应用IHC-P, IP, WB
宿主Mouse
克隆Monoclonal
同位型IgG1
靶点名称EXOSC10 / Rrp6p
抗原物种Human
抗原表位PFRMFLPSLG HRAPVSQAAK FDPSTKIYEI SNRWKLAQVQ VQKDSKEAVK KKAAEQTAAR EQAKEACKAA AEQAISVRQQ VVLENAAKKR ERATSDPRTT EQKQEKKRLK ISKKPKDPEP PEKEFTPYDY SQSDFKAFAG NSKSKVSSQF DPNKQTPSGK
偶联标记Un-conjugated
別名EXOSC10; Exosome Component 10; PM/Scl-100; RRP6; PM-Scl; PMSCL2; Rrp6p; P2; P3; P4; P100 Polymyositis-Scleroderma Overlap Syndrome-Associated Autoantigen; Polymyositis/Scleroderma Autoantigen 100 KDa; Polymyositis/Scleroderma Autoantigen 2; Exosome Complex Component 10; PMSCL; Polymyositis/Scleroderma Autoantigen 2 (100kD); Polymyositis/Scleroderma Autoantigen 2, 100kDa; Autoantigen PM/Scl 2; Autoantigen PM-SCL; EC 3.1.13.-
应用说明
应用建议
应用推荐稀释比
IHC-P1:200
IP1:100
WB1:1000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Protein A purification
缓冲液PBS with 0.09% sodium azide
抗菌剂0.09% sodium azide
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
基因名称EXOSC10
全名Exosome Component 10
背景介绍Enables 3'-5'-exoribonuclease activity. Involved in several processes, including RNA catabolic process; maturation of 5.8S rRNA; and negative regulation of telomere maintenance via telomerase. Located in cytosol; nuclear lumen; and transcriptionally active chromatin. Part of nuclear exosome (RNase complex). [provided by Alliance of Genome Resources, Apr 2022]
生物功能Regulates metabolism of C9orf72-derived repeat RNA that can be translated into toxic dipeptide repeat proteins. [UniProt]
细胞定位Cytoplasm, Exosome, Nucleus. [UniProt]
翻译后修饰Isopeptide bond, Phosphoprotein, Ubl conjugation. [UniProt]
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