anti-EZH2 antibody [SQab30336]

CAT.NO. : ARG67066

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Size:

100 μl

*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	Recombinant Rabbit Monoclonal antibody [SQab30336] recognizes EZH2
反应物种	Hu
应用	IHC-P
宿主	Rabbit
克隆	Monoclonal
克隆号	SQab30336
同位型	IgG
靶点名称	EZH2
抗原物种	Human
抗原	Recombinant protein fragment of EZH2
偶联标记	Un-conjugated
Protein Full name	EZH2
別名	EZH2 ; Enhancer Of Zeste 2 Polycomb Repressive Complex 2 Subunit; ENX-1; KMT6 ; KMT6A; Histone-Lysine N-Methyltransferase EZH2; Lysine N-Methyltransferase 6; Enhancer Of Zeste Homolog 2; EZH1; Enhancer Of Zeste (Drosophila) Homolog 2; Enhancer Of Zeste Homolog 2 (Drosophila) 2 EC 2.1.1.43'); EC 2.1.1.356; EC 2.1.1.43; EC 2.1.1; EZH2b; ENX1; WVS2; WVS

应用说明

应用建议

应用	推荐稀释比
IHC-P	1:100-1:200

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purification with Protein A.
缓冲液	PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA.
抗菌剂	0.01% Sodium azide
稳定剂	40% Glycerol and 0.05% BSA
存放说明	-20°C
注意事项	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.

生物信息

数据库连接	GeneID: 2146 Human EZH2 Swiss-port # Q15910 Human Histone-lysine N-methyltransferase EZH2
基因名称	EZH2
全名	enhancer of zeste 2 polycomb repressive complex 2 subunit
背景介绍	This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Feb 2011]
生物功能	Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Displays a preference for substrates with less methylation, loses activity when progressively more methyl groups are incorporated into H3K27, H3K27me0 > H3K27me1 > H3K27me2. [UniProt]
细胞定位	Nucleus. [UniProt]
预测分子量	85 kDa
翻译后修饰	Glycoprotein, Isopeptide bond, Phosphoprotein,Ubl conjugation. [UniProt]

检测图片 (1)

ARG67066 anti-EZH2 antibody [SQab30336] IHC-P image
Immunohistochemistry: Human testis tissue stained with ARG67066 anti-EZH2 antibody [SQab30336] at 1:100 dilution.

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