anti-Factor D antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes Factor D
  • 反应物种: Hu, Ms
  • 应用: WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: Factor D
  • 抗原物种: Human
  • 抗原: Recombinant fusion protein corresponding to aa. 26-253 of Human Factor D (NP_001919.2).
  • Brand:
CAT.NO. : ARG58485
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes Factor D
反应物种Hu, Ms
应用WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称Factor D
抗原物种Human
抗原Recombinant fusion protein corresponding to aa. 26-253 of Human Factor D (NP_001919.2).
偶联标记Un-conjugated
別名C3 convertase activator; PFD; Properdin factor D; DF; Complement factor D; ADIPSIN; EC 3.4.21.46; ADN; Adipsin
应用说明
应用建议
应用推荐稀释比
WB1:500 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照Mouse lung
实际分子量27 kDa
属性
形式Liquid
纯化Affinity purified.
缓冲液PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 11537 Mouse CFD

GeneID: 1675 Human CFD

Swiss-port # P00746 Human Complement factor D

Swiss-port # P03953 Mouse Complement factor D

基因名称CFD
全名complement factor D (adipsin)
背景介绍The protein encoded by this gene is a member of the trypsin family of peptidases. The encoded protein is a component of the alternative complement pathway best known for its role in humoral suppression of infectious agents. This protein is also a serine protease that is secreted by adipocytes into the bloodstream. Finally, the encoded protein has a high level of expression in fat, suggesting a role for adipose tissue in immune system biology. [provided by RefSeq, Jul 2008]
生物功能Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway. [UniProt]
细胞定位Secreted. [UniProt]
预测分子量27 kDa
检测图片 (1)
  • ARG58485 anti-Factor D antibody WB image

    Western blot: 25 µg of Mouse lung lysate stained with ARG58485 anti-Factor D antibody at 1:1000 dilution.

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