anti-FADS2 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes FADS2
  • 反应物种: Hu, Ms, Rat
  • 应用: WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: FADS2
  • 抗原物种: Human
  • 抗原: Recombinant protein of Human FADS2.
  • Brand:
CAT.NO. : ARG57281
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes FADS2
反应物种Hu, Ms, Rat
应用WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称FADS2
抗原物种Human
抗原Recombinant protein of Human FADS2.
偶联标记Un-conjugated
別名Delta-6 desaturase; FADSD6; D6D; DES6; Fatty acid desaturase 2; LLCDL2; EC 1.14.19.-; SLL0262; TU13
应用说明
应用建议
应用推荐稀释比
WB1:1000 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照U87
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 56473 Mouse FADS2

GeneID: 83512 Rat FADS2

GeneID: 9415 Human FADS2

基因名称FADS2
全名fatty acid desaturase 2
背景介绍The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]
生物功能Component of a lipid metabolic pathway that catalyzes biosynthesis of highly unsaturated fatty acids (HUFA) from precursor essential polyunsaturated fatty acids (PUFA) linoleic acid (LA) (18:2n-6) and alpha-linolenic acid (ALA) (18:3n-3). Catalyzes the first and rate limiting step in this pathway which is the desaturation of LA (18:2n-6) and ALA (18:3n-3) into gamma-linoleic acid (GLA) (18:3n-6) and stearidonic acid (18:4n-3) respectively and other desaturation steps. Highly unsaturated fatty acids (HUFA) play pivotal roles in many biological functions. It catalizes as well the introduction of a cis double bond in palmitate to produce the mono-unsaturated fatty acid sapienate, the most abundant fatty acid in sebum. [UniProt]
预测分子量52 kDa
检测图片 (1)
  • ARG57281 anti-FADS2 antibody WB image

    Western blot: U87 cell lysate stained with ARG57281 anti-FADS2 antibody.

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