anti-FAM120A antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes FAM120A
  • 反应物种: Hu, Rat
  • 预测物种: Ms
  • 应用: ICC/IF, IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: FAM120A
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG43424
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes FAM120A
反应物种Hu, Rat
预测物种Ms
应用ICC/IF, IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称FAM120A
抗原物种Human
抗原An 18-amino acid synthetic peptide within aa. 610-660 of Human FAM120A.
偶联标记Un-conjugated
別名Constitutive coactivator of PPAR-gamma-like protein 1; Protein FAM120A; C9orf10; Oxidative stress-associated Src activator; DNAPTP5; DNAPTP1; OSSA
应用说明
应用建议
应用推荐稀释比
ICC/IF20 µg/ml
IHC-P2.5 µg/ml
WB0.5 - 1 µg/ml
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照SK-N-SH
实际分子量~ 130 kDa
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液PBS and 0.02% Sodium azide.
抗菌剂0.02% Sodium azide
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 23196 Human FAM120A

Swiss-port # Q9NZB2 Human Constitutive coactivator of PPAR-gamma-like protein 1

基因名称FAM120A
全名family with sequence similarity 120A
生物功能May participate in mRNA transport in the cytoplasm (By similarity). Critical component of the oxidative stress-induced survival signaling. Activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. Binds RNA and promotes the secretion of IGF-II. May play a pivotal role in the progression of scirrhous-type gastric cancer by supporting cancer cell survival in environments with various oxidative stresses. [UniProt]
细胞定位Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Translocates to plasma membrane upon ultraviolet exposure. [UniProt]
预测分子量122 kDa
翻译后修饰Arg-982 is dimethylated, probably to asymmetric dimethylarginine.

Phosphorylated on tyrosine by src family kinases upon ultraviolet exposure. [UniProt]
检测图片 (3)
  • ARG43424 anti-FAM120A antibody ICC/IF image

    Immunofluorescence: Rat brain cells stained with ARG43424 anti-FAM120A antibody at 20 µg/ml dilution.

  • ARG43424 anti-FAM120A antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Rat brain tissue stained with ARG43424 anti-FAM120A antibody at 2.5 µg/ml dilution.

  • ARG43424 anti-FAM120A antibody WB image

    Western blot: SK-N-SH cell lysate stained with ARG43424 anti-FAM120A antibody at 0.5 µg/ml dilution.

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