anti-FANCC antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG58607
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes FANCC |
|---|---|
| 反应物种 | Hu |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | FANCC |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide between aa. 527-555 of Human FANCC. |
| 偶联标记 | Un-conjugated |
| 別名 | FA3; FACC; Protein FACC; Fanconi anemia group C protein; FAC |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | HepG2 |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A and immunogen peptide. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide. |
| 抗菌剂 | 0.09% (W/V) Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | FANCC |
| 全名 | Fanconi anemia, complementation group C |
| 背景介绍 | The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group C. [provided by RefSeq, Jul 2008] |
| 生物功能 | DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1. [UniProt] |
| 细胞定位 | Nucleus. Cytoplasm. Note=The major form is nuclear. The minor form is cytoplasmic. [UniProt] |
| 预测分子量 | 63 kDa |
检测图片 (2)
ARG58607 anti-FANCC antibody ICC/IF image
Immunofluorescence: U251 cells stained with ARG58607 anti-FANCC antibody (green) at 1:25 dilution. DAPI (blue) for nuclear staining.
ARG58607 anti-FANCC antibody WB image
Western blot: 35 µg of HepG2 cell lysate stained with ARG58607 anti-FANCC antibody at 1:1000 dilution.
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