anti-Fatso antibody [5-2H10]
![anti-Fatso antibody [5-2H10]](/upload/image/products/ARG52285_WB_181025_210_205.jpg)
![anti-Fatso antibody [5-2H10]](/upload/image/products/ARG52285_WB_181025.jpg)
Key features and details
- 产品描述:
- 反应物种:
- 预测物种:
- 应用:
- 宿主:
- 克隆:
- 克隆号:
- 同位型:
- 靶点名称:
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Brand:
CAT.NO. : ARG52285
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Product Details
概述
| 产品描述 | Mouse Monoclonal antibody [5-2H10] recognizes Fatso |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 预测物种 | Bov, Dog, Hrs, NHuPrm, Sheep |
| 应用 | ICC/IF, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 5-2H10 |
| 同位型 | IgG |
| 靶点名称 | Fatso |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH |
| 偶联标记 | Un-conjugated |
| 別名 | EC 1.14.11.-; Alpha-ketoglutarate-dependent dioxygenase FTO; Fat mass and obesity-associated protein; ALKBH9 |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | Specific for the ~58 kDa Fto protein in Western blots of Rat testes lysate. The antibody has also been used for immunocytochemistry with neuronal progenitor cells. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein G purified |
| 缓冲液 | 10 mM HEPES (pH 7.5), 150 mM NaCl, 0.1 mg/ml BSA and 50% Glycerol |
| 稳定剂 | 0.1 mg/ml BSA, 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | FTO |
| 全名 | fat mass and obesity associated |
| 背景介绍 | The FTO gene is the most robust gene for common obesity characterized to date. FTO gene expression has been found to be significantly upregulated in the hypothalamus of rats after food deprivation and strongly negatively correlated with the expression of orexin peptide which is involved in the stimulation of food intake (Fredricksson R et al., 2008). Deletion analysis of FTO gene in mice showed that Fto is functionally involved in the control of both energy intake and energy expenditure (Fischer J et al., 2009) |
| 研究领域 | Cell Biology and Cellular Response antibody; Metabolism antibody; Neuroscience antibody |
| 预测分子量 | 58 kDa |
检测图片 (1)
ARG52285 anti-Fatso antibody [5-2H10] WB image
Western blot: Rat testis lysate showing specific immunolabeling of the ~ 58 kDa Fatso protein stained with ARG52285 anti-Fatso antibody [5-2H10].
参考文献
克隆号文献
FTO levels affect RNA modification and the transcriptome.
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