anti-FBXO32 antibody
Key features and details
- 产品描述:
- 反应物种:
- 预测物种:
- 应用:
- 特异性:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
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Brand:
CAT.NO. : ARG64846
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Product Details
概述
| 产品描述 | Goat Polyclonal antibody recognizes FBXO32 |
|---|---|
| 反应物种 | Ms |
| 预测物种 | Hu, Rat, Cow, Pig |
| 应用 | WB |
| 特异性 | This antibody is expected to recognize reported isoform 1 (NP_478136.1). |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | FBXO32 |
| 抗原物种 | Human |
| 抗原 | C-NSKTKTQYFHQEK |
| 偶联标记 | Un-conjugated |
| 別名 | Muscle atrophy F-box protein; Atrogin-1; F-box only protein 32; Fbx32; MAFbx |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 背景介绍 | This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011] |
| 研究领域 | Cell Biology and Cellular Response antibody; Developmental Biology antibody |
| 预测分子量 | 42 kDa |
检测图片 (2)
ARG64846 anti-FBXO32 antibody WB image
Western Blot: Human Skeletal Muscle lysate (35 µg protein in RIPA buffer) stained with ARG64846 anti-FBXO32 antibody at 1 µg/ml dilution.
ARG64846 anti-FBXO32 antibody WB image
Western blot: 35 µg of Mouse skeletal muscle lysate (in RIPA buffer) stained with ARG64846 anti-FBXO32 antibody at 0.3 µg/ml dilution and incubated at RT for 1 hour.
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