anti-FCGRT antibody [SQab30340]

Key features and details

  • 产品描述: Recombinant Rabbit Monoclonal antibody [SQab30340] recognizes FCGRT
  • 反应物种: Hu
  • 应用: IHC-P
  • 宿主: Rabbit
  • 克隆: Monoclonal
  • 克隆号: SQab30340
  • 同位型: IgG
  • 靶点名称: FCGRT
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG67058
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Product Details
概述
产品描述Recombinant Rabbit Monoclonal antibody [SQab30340] recognizes FCGRT
反应物种Hu
应用IHC-P
宿主Rabbit
克隆Monoclonal
克隆号SQab30340
同位型IgG
靶点名称FCGRT
抗原物种Human
抗原Recombinant protein fragment of FCGRT
偶联标记Un-conjugated
Protein Full nameIgG receptor FcRn large subunit p51
別名FCGRT; Fc Gamma Receptor And Transporter ; Neonatal Fc Receptor; FcgammaRn; FcRn; Heavy Chain Of The Major Histocompatibility Complex Class I-Like Fc Receptor; Transmembrane Alpha Chain Of The Neonatal Receptor; Fc Fragment Of IgG, Receptor, Transporter, Alpha; IgG Fc Fragment Receptor Transporter Alpha Chain; Fc Fragment Of IgG Receptor And Transporter; IgG Receptor FcRn Large Subunit P51; FCRN; Major Histocompatibility Complex Class I-Like Fc Receptor; Immunoglobulin Receptor, Intestinal, Heavy Chain; Neonatal Fc-Receptor For Ig; FCRN Alpha-Chain; FcRn Alpha Chai; Alpha-Chain
应用说明
应用建议
应用推荐稀释比
IHC-P1:100-1:200
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purification with Protein A.
缓冲液PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA.
抗菌剂0.01% Sodium azide
稳定剂40% Glycerol and 0.05% BSA
存放说明-20°C
注意事项For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
生物信息
数据库连接

GeneID: 2217 Human FCGRT

Swiss-port # P55899 Human IgG receptor FcRn large subunit p51

基因名称FCGRT
全名Fc Gamma Receptor And Transporter
背景介绍This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]
生物功能IgG in the milk is bound at the apical surface of the intestinal epithelium. The resultant FcRn-IgG complexes are transcytosed across the intestinal epithelium and IgG is released from FcRn into blood or tissue fluids. Throughout life, contributes to effective humoral immunity by recycling IgG and extending its half-life in the circulation. Mechanistically, monomeric IgG binding to FcRn in acidic endosomes of endothelial and hematopoietic cells recycles IgG to the cell surface where it is released into the circulation.
细胞定位Cell membrane, Endosome, Membrane. [UniProt]
翻译后修饰Disulfide bond, Glycoprotein, Phosphoprotein. [UniProt]
检测图片 (1)
  • ARG67058 anti-FCGRT antibody [SQab30340] IHC-P image

    Immunohistochemistry: Human tonsil tissue stained with ARG67058anti-FCGRT antibody [SQab30340] at 1:100 dilution.

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