anti-Ferritin Heavy Chain antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes Ferritin Heavy Chain
  • 反应物种: Hu, Ms, Rat
  • 应用: ICC/IF, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: Ferritin Heavy Chain
  • 抗原物种: Human
  • 抗原: Synthetic peptide of Human Ferritin.
  • Brand:
CAT.NO. : ARG41439
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes Ferritin Heavy Chain
反应物种Hu, Ms, Rat
应用ICC/IF, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称Ferritin Heavy Chain
抗原物种Human
抗原Synthetic peptide of Human Ferritin.
偶联标记Un-conjugated
別名Cell proliferation-inducing gene 15 protein; HFE5; FHC; PIG15; PLIF; Ferritin H subunit; FTH; Ferritin heavy chain; EC 1.16.3.1; FTHL6
应用说明
应用建议
应用推荐稀释比
ICC/IF1:50 - 1:200
WB1:500 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照Jurkat
实际分子量~ 20 kDa
属性
形式Liquid
纯化Affinity purified.
缓冲液PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 14319 Mouse FTH1

GeneID: 2495 Human FTH1

GeneID: 25319 Rat FTH1

基因名称FTH1
全名ferritin, heavy polypeptide 1
背景介绍This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
生物功能Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity). [UniProt]
预测分子量21 kDa
检测图片 (2)
  • ARG41439 anti-Ferritin antibody ICC/IF image

    Immunofluorescence: Jurkat cells stained with ARG41439 anti-Ferritin antibody.

  • ARG41439 anti-Ferritin antibody WB image

    Western blot: Jurkat cell lysate stained with ARG41439 anti-Ferritin antibody.

参考文献

Inhibition of circRNA NGFR promotes ferroptosis in gallbladder carcinoma cells

WB / Human

Desen Fan et al.
Heliyon.,  (2024)

publication_link

 

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