anti-FGF12 antibody

Key features and details

  • 产品描述: Mouse Monoclonal antibody recognizes FGF12
  • 反应物种: Hu, Ms, Rat
  • 应用: IP, WB
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 同位型: IgG1
  • 靶点名称: FGF12
  • 抗原物种: Human
  • 偶联标记: Un-conjugated
  • Brand:
CAT.NO. : ARG44659
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Product Details
概述
产品描述Mouse Monoclonal antibody recognizes FGF12
反应物种Hu, Ms, Rat
应用IP, WB
宿主Mouse
克隆Monoclonal
同位型IgG1
靶点名称FGF12
抗原物种Human
偶联标记Un-conjugated
別名FGF12; Fibroblast Growth Factor 12; FHF1; Fibroblast Growth Factor Homologous Factor 1; Myocyte-Activating Factor; FGF12B; Fibroblast Growth Factor FGF-12b; Fibroblast Growth Factor 12B; EIEE47; FGF-12; DEE47; FHF-1
应用说明
应用建议
应用推荐稀释比
IP10 µg/mL
WB1 µg/mL
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Protein A purification
缓冲液PBS with 0.09% sodium azide
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 14167 Mouse FGF12

GeneID: 170630 Rat FGF12

GeneID: 2257 Human FGF12

基因名称FGF12
全名Fibroblast Growth Factor 12
背景介绍The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This growth factor lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfected into mammalian cells, this protein accumulated in the nucleus, but was not secreted. The specific function of this gene has not yet been determined. [provided by RefSeq, Dec 2019]
生物功能Involved in nervous system development and function. Involved in the positive regulation of voltage-gated sodium channel activity. Promotes neuronal excitability by elevating the voltage dependence of neuronal sodium channel SCN8A fast inactivation. [UniProt]
细胞定位Nucleus. [UniProt]
检测图片 (4)
  • ARG44659 anti-FGF12 antibody WB image

    Western blot: Human Brain stained with ARG44659 anti-FGF12 antibody at 1 µg/mL dilution.

  • ARG44659 anti-FGF12 antibody IP image

    Immunoprecipitation: Rat Brain lysate immunoprecipitated with 2.5 µg of ARG44659 anti-FGF12 antibody.

  • ARG44659 anti-FGF12 antibody WB image

    Western blot: Rat Brain stained with ARG44659 anti-FGF12 antibody at 1 µg/mL dilution.

  • ARG44659 anti-FGF12 antibody WB image

    Western blot: Mouse Brain stained with ARG44659 anti-FGF12 antibody at 1 µg/mL dilution.

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