anti-Fibrillin 1 antibody [RM463]
![anti-Fibrillin 1 antibody [RM463]](/upload/image/20241105/8415bc38bc270b898ee2a90369a6c7fb.jpg)
Key features and details
- 产品描述:
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- 应用:
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- 宿主:
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- 同位型:
- 靶点名称:
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Brand:
CAT.NO. : ARG45049
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Product Details
概述
| 产品描述 | Rabbit monoclonal [RM463] recognizes Fibrillin 1. |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, WB |
| 特异性 | This antibody reacts to human Asprosin. |
| 宿主 | Rabbit |
| 克隆 | Monoclonal |
| 克隆号 | RM463 |
| 同位型 | IgG |
| 靶点名称 | Fibrillin 1 |
| 抗原 | Recombinant full-length human Asprosin protein |
| 偶联标记 | Un-conjugated |
| 別名 | FBN1 ; Fibrillin 1; MASS; OCTD; SGS; FBN; Fibrillin-1; Asprosin; MFS1; WMS; Epididymis Secretory Sperm Binding Protein; Fibrillin 1 (Marfan Syndrome); Fibrillin-1 Preproprotein; Marfan Syndrome; Fibrillin 15; GPHYSD2; ACMICD; ECTOL1; MFLS; SSKS; WMS2 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS with 50% Glycerol, 1% BSA and 0.09% sodium azide |
| 抗菌剂 | 0.09% sodium azide |
| 稳定剂 | 50% Glycerol, 1% BSA and 0.09% |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | FBN1 |
| 全名 | Fibrillin 1 |
| 背景介绍 | This gene encodes a member of the fibrillin family of proteins. The encoded preproprotein is proteolytically processed to generate two proteins including the extracellular matrix component fibrillin-1 and the protein hormone asprosin. Fibrillin-1 is an extracellular matrix glycoprotein that serves as a structural component of calcium-binding microfibrils. These microfibrils provide force-bearing structural support in elastic and nonelastic connective tissue throughout the body. Asprosin, secreted by white adipose tissue, has been shown to regulate glucose homeostasis. Mutations in this gene are associated with Marfan syndrome and the related MASS phenotype, as well as ectopia lentis syndrome, Weill-Marchesani syndrome, Shprintzen-Goldberg syndrome and neonatal progeroid syndrome. [provided by RefSeq, Apr 2016] |
| 生物功能 | May also play a role in sperm motility in testis via interaction with OR4M1 receptor |
| 细胞定位 | Extracellular matrix, Secreted |
| 翻译后修饰 | Disulfide bond, Glycoprotein, Phosphoprotein |
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