anti-FIV gp95 antibody [SU1-30]
![anti-FIV gp95 antibody [SU1-30]](/upload/image/20241105/8415bc38bc270b898ee2a90369a6c7fb.jpg)
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 克隆号:
- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
CAT.NO. : ARG23158
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Product Details
概述
| 产品描述 | Mouse Monoclonal antibody [SU1-30] recognizes FIV gp95 Mouse anti Feline Immunodeficiency Virus gp95 antibody, clone SU1-30 recognizes the relatively conserved E60 peptide (amino acid sequence SSWKQRNRWEWRPDF) located within the V3 region of FIV (Feline Immunodeficiency Virus) envelope glycoprotein SU,gp95. The primary receptor for FIV infection of cats has been identified as the T-cell activation antigen CD134 which, along with CXC chemokine receptor 4 (CXCR4), facilitates the infection of CD4+ primary target cells, resulting in a depletion in the CD4+ population. Studies have shown that the V3 loop of SU,gp95 is a major immunogenic domain, suggested to contain the main determinants for the binding of FIV SU,gp95 to CXCR4 (Sundstrom, M. et al. 2008).Mouse anti Feline Immunodeficiency Virus gp95 antibody, clone SU1-30 has been shown to inhibit the sCD134-activated entry of both clade B and clade C FIV strains (de Parseval, A. et al. 2006). Mouse anti Feline Immunodeficiency Virus gp95 antibody, clone SU1-30 does not recognise Feline Leukaemia Virus, Feline Herpes Virus type 1, Feline Coronavirus or Feline Calicivirus. Removal of Sodium Azide is recommended prior to use in functional studies - The use of EQU003 is recommended for this purpose. |
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| 反应物种 | Virus |
| 应用 | FACS, FuncSt, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | SU1-30 |
| 同位型 | IgG1 |
| 靶点名称 | FIV gp95 |
| 抗原物种 | Virus |
| 偶联标记 | Un-conjugated |
应用说明
| 应用建议 |
| ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | FACS: Use 10 µl of the suggested working dilution to label 10^6 cells in 100 µl. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS and 0.05% Sodium azide. |
| 抗菌剂 | 0.05% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
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