anti-FMO5 antibody
Key features and details
- 产品描述:
- 反应物种:
- 预测物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
CAT.NO. : ARG58755
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes FMO5 |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms, Rat, Cow, Dog, Gpig, Hrs, Rb |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | FMO5 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide around the middle region of Human FMO5. (within the following sequence: NKYLEKKINQRFDHEMFGLKPKHRALSQHPTLNDDLPNRIISGLVKVKGN) |
| 偶联标记 | Un-conjugated |
| 別名 | Dimethylaniline monooxygenase [N-oxide-forming] 5; FMO 5; Hepatic flavin-containing monooxygenase 5; EC 1.14.13.8; Dimethylaniline oxidase 5 |
应用说明
| 预测反应性说明 | Predicted homology based on immunogen sequence: Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100% | ||||||
|---|---|---|---|---|---|---|---|
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | HeLa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS, 0.09% (w/v) Sodium azide and 2% Sucrose. |
| 抗菌剂 | 0.09% (w/v) Sodium azide |
| 稳定剂 | 2% Sucrose |
| 浓度 | Batch dependent: 0.5 - 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # P49326 Human Dimethylaniline monooxygenase [N-oxide-forming] 5 |
|---|---|
| 基因名称 | FMO5 |
| 全名 | flavin containing monooxygenase 5 |
| 背景介绍 | Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009] |
| 生物功能 | In contrast with other forms of FMO it does not seem to be a drug-metabolizing enzyme. [UniProt] |
| 预测分子量 | 60 kDa |
检测图片 (2)
ARG58755 anti-FMO5 antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Human liver stained with ARG58755 anti-FMO5 antibody at 1:600 dilution. Magnification: 20X.
ARG58755 anti-FMO5 antibody WB image
Western blot: HeLa cell lysate stained with ARG58755 anti-FMO5 antibody at 0.2 - 1 µg/ml dilution.
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