anti-FNDC5 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes FNDC5
  • 反应物种: Hu, Ms
  • 应用: IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: FNDC5
  • 抗原物种: Human
  • 抗原: Synthetic peptide within the extracellular domain of Human FNDC5.
  • Brand:
CAT.NO. : ARG66990
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes FNDC5
反应物种Hu, Ms
应用IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称FNDC5
抗原物种Human
抗原Synthetic peptide within the extracellular domain of Human FNDC5.
偶联标记Un-conjugated
別名irisin; FRCP2; Fibronectin type III domain-containing protein 5; Fibronectin type III repeat-containing protein 2
应用说明
应用建议
应用推荐稀释比
IHC-P1:300 - 1:600
WB1:500 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
实际分子量20-25 kDa
属性
形式Liquid
纯化Affinity purified.
缓冲液100 mM Tris Glycine (pH 7.0), 0.025% ProClin 300 and 20% Glycerol.
抗菌剂0.025% ProClin 300
稳定剂20% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 252995 Human FNDC5

GeneID: 384061 Mouse FNDC5

Swiss-port # Q8K4Z2 Mouse Fibronectin type III domain-containing protein 5

Swiss-port # Q8NAU1 Human Fibronectin type III domain-containing protein 5

基因名称FNDC5
全名fibronectin type III domain containing 5
背景介绍This gene encodes a secreted protein that is released from muscle cells during exercise. The encoded protein may participate in the development of brown fat. Translation of the precursor protein initiates at a non-AUG start codon at a position that is conserved as an AUG start codon in other organisms. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
生物功能Irisin: Contrary to mouse, may not be involved in the beneficial effects of muscular exercise, nor in the induction of browning of human white adipose tissue. [UniProt]
细胞定位Cell membrane. [UniProt]
预测分子量23 kDa
翻译后修饰The extracellular domain is cleaved and released from the cell membrane.

N-Glycosylated. [UniProt]
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