anti-FOX3 / NeuN antibody [1B7]
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Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 克隆号:
- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
Product Details
| 产品描述 | Mouse Monoclonal antibody [1B7] recognizes FOX3 / NeuN |
|---|---|
| 反应物种 | Hu, Ms, Rat, Bov, Cat, Chk, Dog, Goat, Pig |
| 应用 | ICC/IF, IHC-Fr, IHC-P, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 1B7 |
| 同位型 | IgG2a |
| 靶点名称 | FOX3 / NeuN |
| 抗原物种 | Human |
| 抗原 | Recombinant protein taken from the N-terminus of human FOX3 expressed in and purified from E. Coli |
| 偶联标记 | Un-conjugated |
| 別名 | RNA binding protein fox-1 homolog 3; NEUN; FOX-3; HRNBP3; Fox-1 homolog C; FOX3 |
| 应用建议 |
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|---|---|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | Specific for the ~46/48k FOX3 protein doublet * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity Purified |
| 缓冲液 | PBS and 10 mM Sodium azide. |
| 抗菌剂 | 10 mM Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
| 数据库连接 | |
|---|---|
| 基因名称 | RBFOX3 |
| 全名 | RNA binding protein, fox-1 homolog (C. elegans) 3 |
| 背景介绍 | FOX3, also known as NeuN and hexaribonucleotide binding protein 3, is a neuron-specific RNA binding nuclear protein involved in the regulation of pre-mRNA alternative splicing (Kim et al., 2009). FOX3 dependent alternative splicing of Numb has recently been shown to play an important role in the progression of neuronal differentiation during vertebrate development (Kim et al., 2013). |
| 产品亮点 | Related products: FOX3 antibodies; Anti-Mouse IgG secondary antibodies; Related news: Stem cell and the regenerative medicine: Ready for the patients Neuronal Development Marker |
| 研究领域 | Controls and Markers antibody; Gene Regulation antibody; Neuroscience antibody |
| 预测分子量 | 34 kDa |
ARG52283 anti-FOX3 / NeuN antibody [1B7] ICC/IF image
Immunofluorescence: Cultured Rat neurons stained with ARG52283 anti-FOX3 / NeuN antibody [1B7] showing strong nuclear and distal cytoplasmic staining of FOX3 in red and the complete absence of astrocyte staining, which are stained in green with ARG52313 anti-GFAP antibody.
ARG52283 anti-FOX3 / NeuN antibody [1B7] IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Rat brain stem neurons stained with ARG52283 anti-FOX3 / NeuN antibody [1B7] (green) and counter stained with anti-MAP2 antibody (red). The nuclei of cells are revealed with DAPI in blue.
ARG52283 anti-FOX3 / NeuN antibody [1B7] WB image
Western Blot: Rat cortex lysate showing specific immunolabeling of the ~46/48k FOX3 protein stained with ARG52283 anti-FOX3 / NeuN antibody [1B7].
ARG52283 anti-FOX3 / NeuN antibody [1B7] WB image
Western blot: Rat brain, Rat brain (embryonic, E20) and Mouse brain lysates stained with ARG52283 anti-FOX3 / NeuN antibody [1B7] (green) at 1:1000 dilution.
ARG52283 anti-FOX3 / NeuN antibody [1B7] IHC-FoFr image
Immunohistochemistry: Adult Rat hippocampus stainedwith anti-c-Fos antibody (red) and DNA (blue). ARG52283 anti-FOX3 / NeuN antibody [1B7] (green) reveals strongnuclear and distal cytoplasmic staining for hippocampal neurons and the complete absence of staining of nonneuronal cells.
A few spontaneously active cells show in addition expression of c-Fos (arrowed). ARG52283 is therefore and excellent marker of neuronal activation.
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