anti-FOXC2 antibody

Key features and details

  • 产品描述: Goat Polyclonal antibody recognizes FOXC2
  • 反应物种: Hu
  • 预测物种: Cow, Rat, Dog
  • 应用: FACS, IHC-P, WB
  • 宿主: Goat
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: FOXC2
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG63332
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Product Details
概述
产品描述Goat Polyclonal antibody recognizes FOXC2
反应物种Hu
预测物种Cow, Rat, Dog
应用FACS, IHC-P, WB
宿主Goat
克隆Polyclonal
同位型IgG
靶点名称FOXC2
抗原物种Human
抗原RHAAPYSYDCTKY
偶联标记Un-conjugated
別名LD; FKHL14; Transcription factor FKH-14; Forkhead box protein C2; MFH-1; MFH1; MFH-1 protein; Mesenchyme fork head protein 1; Forkhead-related protein FKHL14
应用说明
应用建议
应用推荐稀释比
FACS10 µg/ml
IHC-PAssay-dependent
WB1 - 2 µg/ml
应用说明WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 2303 Human FOXC2

Swiss-port # Q99958 Human Forkhead box protein C2

背景介绍This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in the development of mesenchymal tissues. [provided by RefSeq, Jul 2008]
产品亮点Related Antibody Duos and Panels:
ARG30314 Chondrogenesis Marker Antibody Panel
Related products:
FOXC2 antibodies; FOXC2 Duos / Panels; Anti-Goat IgG secondary antibodies;
研究领域Developmental Biology antibody; Gene Regulation antibody; Metabolism antibody; Chondrogenesis Study antibody
预测分子量54 kDa
翻译后修饰Phosphorylation regulates FOXC2 transcriptional activity by promoting its recruitment to chromatin.
检测图片 (2)
  • ARG63332 anti-FOXC2 antibody WB image

    Western blot: 35 µg of HEK293 nucleus (A) and Human pancreas (B, negative control) lysates (in RIPA buffer) stained with ARG63332 anti-FOXC2 antibody at 2 µg/ml (A) and 1 µg/ml (B) dilutions and incubated at RT for 1 hour.

  • ARG63332 anti-FOXC2 antibody FACS image

    Flow Cytometry: Paraformaldehyde-fixed HEK293 cells permeabilized with 0.5% Triton. Cells were stained with ARG63332 anti-FOXC2 antibody (blue line) at 10 µg/ml dilution for 1 hour, followed by incubation with Alexa FluorR 488 labelled secondary antibody. IgG control: Unimmunized goat IgG (black line).

参考文献

Expression and clinical significance of FOXC2 and E-cad in colon cancer tissues (FOXC2和E-cad在结肠癌组织中的表达及临床意义)

IHC-P / Human

Wang Jing-Miao (王静苗) et al.
Chinese Clinical Oncology (临床肿瘤学杂志), 21(8),  (2016)

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