anti-FOXP3 antibody [SP97]

Key features and details

  • 产品描述: Rabbit Monoclonal antibody [SP97] recognizes FOXP3
  • 反应物种: Hu
  • 应用: IHC-P
  • 宿主: Rabbit
  • 克隆: Monoclonal
  • 克隆号: SP97
  • 同位型: IgG
  • 靶点名称: FOXP3
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG53050
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Product Details
概述
产品描述Rabbit Monoclonal antibody [SP97] recognizes FOXP3
反应物种Hu
应用IHC-P
宿主Rabbit
克隆Monoclonal
克隆号SP97
同位型IgG
靶点名称FOXP3
抗原物种Human
抗原Synthetic peptide corresponding to C-terminus of human FOXP3 protein.
偶联标记Un-conjugated
別名FOXP3; Forkhead Box P3; DIETER; XPID; AIID; PIDX; IPEX; JM2; Immune Dysregulation, Polyendocrinopathy, Enteropathy, X-Linked; Forkhead Box Protein P3; SCURFIN; Immunodeficiency, Polyendocrinopathy, Enteropathy, X-Linked; FOXP3delta7; Scurfin
应用说明
应用建议
应用推荐稀释比
IHC-P1:100
应用说明IHC-P: Antigen Retrieval: Boil tissue section in EDTA buffer, pH 8.0 for 10 min followed by cooling at room temperature for 20 min.
Incubation Time: 20 min at RT.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照Tonsil
属性
形式Liquid
纯化Purified by protein A/G
缓冲液PBS (pH 7.6), 1% BSA and
抗菌剂
稳定剂1% BSA
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 50943 Human FOXP3

Swiss-port # Q9BZS1 Human Forkhead box protein P3

基因名称FOXP3
全名forkhead box P3
背景介绍The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
生物功能Transcriptional regulator which is crucial for the development and inhibitory function of regulatory T-cells (Treg). [UniProt]

Plays an essential role in maintaining homeostasis of the immune system by allowing the acquisition of full suppressive function and stability of the Treg lineage, and by directly modulating the expansion and function of conventional T-cells. [UniProt]
细胞定位Cytoplasm, Nucleus. [UniProt]
产品亮点Related products:
FOXP3 antibodies; FOXP3 Duos / Panels; Anti-Rabbit IgG secondary antibodies;
Related news:
Tumor-Infiltrating Lymphocytes (TILs)
研究领域Cell Biology and Cellular Response antibody; Gene Regulation antibody; Immune System antibody; Regulatory T cells Study antibody
预测分子量47 kDa
翻译后修饰Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation. [UniProt]
检测图片 (11)
  • ARG53050 anti-FOXP3 antibody [SP97] WB image

    Western Blot: Tonsil stained with FOXP3 antibody [SP97] (ARG53050)

  • ARG53050 anti-FOXP3 antibody [SP97] IHC-P image

    Immunohistochemistry: Human B Cell Lymphoma stained with FOXP3 antibody [SP97] (ARG53050)

  • ARG53050 anti-FOXP3 antibody [SP97] IHC-P image

    Immunohistochemistry: Human Bladder Transitional Cell Carcinoma stained with FOXP3 antibody [SP97] (ARG53050)

  • ARG53050 anti-FOXP3 antibody [SP97] IHC-P image

    Immunohistochemistry: Human Bladder stained with FOXP3 antibody [SP97] (ARG53050)

  • ARG53050 anti-FOXP3 antibody [SP97] IHC-P image

    Immunohistochemistry: Human Cervical Squamous Cell Carcinoma stained with FOXP3 antibody [SP97] (ARG53050)

  • ARG53050 anti-FOXP3 antibody [SP97] IHC-P image

    Immunohistochemistry: Human Colon Adenocarcinoma stained with FOXP3 antibody [SP97] (ARG53050)

  • ARG53050 anti-FOXP3 antibody [SP97] IHC-P image

    Immunohistochemistry: Human Colon stained with FOXP3 antibody [SP97] (ARG53050)

  • ARG53050 anti-FOXP3 antibody [SP97] IHC-P image

    Immunohistochemistry: Human Lymph Node stained with FOXP3 antibody [SP97] (ARG53050)

  • ARG53050 anti-FOXP3 antibody [SP97] IHC-P image

    Immunohistochemistry: Human Pancreatic Adenocarcinoma stained with FOXP3 antibody [SP97] (ARG53050)

  • ARG53050 anti-FOXP3 antibody [SP97] IHC-P image

    Immunohistochemistry: Human Stomach Adenocarcinoma stained with FOXP3 antibody [SP97] (ARG53050)

  • ARG53050 anti-FOXP3 antibody [SP97] IHC-P image

    Immunohistochemistry: Human Thymus stained with FOXP3 antibody [SP97] (ARG53050)

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