anti-FPR1 antibody
CAT.NO. : ARG66395
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概述
产品描述 | Rabbit Polyclonal antibody recognizes FPR1 |
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反应物种 | Hu |
应用 | ICC/IF, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | FPR1 |
抗原物种 | Human |
抗原 | Synthetic peptide within aa. 130-210 of Human FPR1. |
偶联标记 | Un-conjugated |
別名 | N-formylpeptide chemoattractant receptor; FMLP; fMet-Leu-Phe receptor; N-formyl peptide receptor; FPR; fMLP receptor |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Affinity purification with immunogen. |
缓冲液 | PBS, 0.02% Sodium azide, 50% Glycerol and 0.5% BSA. |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 50% Glycerol and 0.5% BSA |
浓度 | 1 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | FPR1 |
全名 | formyl peptide receptor 1 |
背景介绍 | This gene encodes a G protein-coupled receptor of mammalian phagocytic cells that is a member of the G-protein coupled receptor 1 family. The protein mediates the response of phagocytic cells to invasion of the host by microorganisms and is important in host defense and inflammation.[provided by RefSeq, Jul 2010] |
生物功能 | High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors. Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. [UniProt] |
预测分子量 | 38 kDa |
翻译后修饰 | Phosphorylated; which is necessary for desensitization. [UniProt] |
